1,135 Genomes Reveal the Global Pattern of Polymorphism in Arabidopsis thaliana

1001 Genomes Consortium

Veröffentlichungen: Beitrag in FachzeitschriftArtikelPeer Reviewed

Abstract

Arabidopsis thaliana serves as a model organism for the study of fundamental physiological, cellular, and molecular processes. It has also greatly advanced
our understanding of intraspecific genome variation. We present a detailed map of variation in 1,135 high-quality re-sequenced natural inbred lines representingthe native Eurasian and North African range and recently colonized North America. We identify relict populations that continue to inhabit ancestral habitats, primarily in the Iberian Peninsula. They have mixed with a lineage that has spread to northern latitudes from an unknown glacial refugium and is now found in a much broader spectrum of habitats. Insights into the history of the species and the finescale distribution of genetic diversity provide the basis for full exploitation of A. thaliana natural variation through integration of genomes and epigenomes with molecular and non-molecular phenotypes.
OriginalspracheEnglisch
Seiten (von - bis)481-491
Seitenumfang11
FachzeitschriftCell
Jahrgang166
Ausgabenummer2
DOIs
PublikationsstatusVeröffentlicht - 14 Juli 2016

ÖFOS 2012

  • 106005 Bioinformatik
  • 106013 Genetik
  • 106036 Populationsgenetik

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