A structural model of the human serotonin transporter in an outward-occluded state

Eva Hellsberg; Gerhard Ecker; Anna Weinzinger; Lucy R. Forrest

doi:10.1371/journal.pone.0217377

A structural model of the human serotonin transporter in an outward-occluded state

Eva Hellsberg
, Gerhard Ecker
, Anna Weinzinger
, Lucy R. Forrest (Korresp. Autor*in)

Veröffentlichungen: Beitrag in Fachzeitschrift › Artikel › Peer Reviewed

Originalsprache	Englisch
Aufsatznummer	e0217377
Seitenumfang	25
Fachzeitschrift	PLoS ONE
Jahrgang	14
Ausgabenummer	6
DOIs	https://doi.org/10.1371/journal.pone.0217377
Publikationsstatus	Veröffentlicht - 28 Juni 2019

Fördermittel

This work was funded by the Austrian Science Fund, grant W1232, https://www.fwf.ac.at/ en/ (to EH), and by the Division of Intramural Research of the NIH, National Institute of Neurological Disorders and Stroke, https://www. ninds.nih.gov/ (to LRF). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The computational results presented were obtained using the Vienna Scientific Cluster (VSC). We thank the National Heart Lung and Blood Lobos administrators for technical support, Richard Bradshaw for help with water analysis, Talia Zeppelin and Birgit Schi\u00F8tt (University of Aarhus) for sharing their simulation data, and Gary Rudnick for helpful discussions.

ÖFOS 2012

106006 Biophysik
301402 Neurobiologie

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10.1371/journal.pone.0217377Lizenz: Andere

https://phaidra.univie.ac.at/o:1171844Lizenz: Andere

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Molekulare Arzneistoff-Targets
Hering, S. (Projektleiter*in), Ecker, G. (Co-Projektleiter*in), Maulide, N. (Co-Projektleiter*in), Weinzinger, A. (Co-Projektleiter*in) & Gonzalez Herrero, L. (Co-Projektleiter*in)
1/12/10 → 31/12/22
Projekt: Forschungsförderung

Zitationsweisen

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keywords = "ALTERNATING ACCESS, ANTIDEPRESSANT BINDING-SITE, BACTERIAL HOMOLOG, DIVERSE ANTIDEPRESSANTS, DOPAMINE TRANSPORTER, GENERAL FORCE-FIELD, MONOAMINE TRANSPORTERS, STRUCTURE VALIDATION, TRANSMEMBRANE DOMAIN, X-RAY STRUCTURES",

author = "Eva Hellsberg and Gerhard Ecker and Anna Weinzinger and Forrest, \{Lucy R.\}",

note = "Publisher Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.",

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A structural model of the human serotonin transporter in an outward-occluded state

Fördermittel

ÖFOS 2012

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