Antioxidant Activity of Isoflavones and Biflavones Isolated from Godoya antioquiensis

Birgit Benedek

    Veröffentlichungen: Beitrag in FachzeitschriftArtikelPeer Reviewed

    Abstract

    Two biflavones, ochnaflavone (1) and 2'',3''-dihydroochnaflavone (2), and two isoflavones, 5,7,4¿-trihydroxy-3¿,5¿-dimethoxyisoflavone (piscigenin) (3) and 5,4¿-dihydroxy-7,3¿,5¿-trimethoxyisoflavone (4), a new natural compound, were isolated from the leaves of Godoya antioquiensis (Ochnaceae). Their structures were determined on the basis of spectral data and by comparison with data reported in the literature. The isolated compounds were evaluated for their radical scavenging activity using the NBT/hypoxanthine superoxide and the ¿OH/luminol chemiluminescence methods. The isolated isoflavones were found to exhibit a strong hydroxyl radical scavenging activity and a moderate inhibition of the superoxide anion, whereas the two biflavones were inactive in the superoxide anion assay and showed a low hydroxyl radical scavenging activity.
    OriginalspracheEnglisch
    Seiten (von - bis)661-664
    Seitenumfang4
    FachzeitschriftArzneimittel-Forschung
    Jahrgang56
    Ausgabenummer9
    PublikationsstatusVeröffentlicht - 2006

    ÖFOS 2012

    • 301204 Pharmakognosie

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