Functional RNA Structures in the 3′ UTR of Mosquito-Borne Flaviviruses

Michael Thomas Wolfinger; Roman Wilhelm Ochsenreiter; Ivo Hofacker

doi:10.1201/9781003097679

Functional RNA Structures in the 3′ UTR of Mosquito-Borne Flaviviruses

Michael Thomas Wolfinger, Roman Wilhelm Ochsenreiter, Ivo Hofacker

Veröffentlichungen: Beitrag in Buch › Beitrag in Buch/Sammelband › Peer Reviewed

Abstract

Recent experimental evidence revealed a thorough understanding of the involvement of functional RNA elements in the 3′ untranslated regions (UTRs) of flaviviruses with virus tropism. Comparative genomics and thermodynamic modeling allow for the prediction and functional characterization of homologous structures in phylogenetically related viruses. We provide here a comprehensive overview of evolutionarily conserved RNAs in the 3′ UTRs of mosquito-borne flaviviruses.

Originalsprache	Englisch
Titel	Virus Bioinformatics
Redakteure*innen	Dmitrij Frishman, Manja Marz
Herausgeber (Verlag)	Chapman and Hall/CRC
Seitenumfang	36
ISBN (elektronisch)	9781003097679
DOIs	https://doi.org/10.1201/9781003097679
Publikationsstatus	Veröffentlicht - 2021

ÖFOS 2012

106005 Bioinformatik
106002 Biochemie

Zugriff auf Dokument

10.1201/9781003097679

Zitationsweisen

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abstract = "Recent experimental evidence revealed a thorough understanding of the involvement of functional RNA elements in the 3′ untranslated regions (UTRs) of flaviviruses with virus tropism. Comparative genomics and thermodynamic modeling allow for the prediction and functional characterization of homologous structures in phylogenetically related viruses. We provide here a comprehensive overview of evolutionarily conserved RNAs in the 3′ UTRs of mosquito-borne flaviviruses.",

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AB - Recent experimental evidence revealed a thorough understanding of the involvement of functional RNA elements in the 3′ untranslated regions (UTRs) of flaviviruses with virus tropism. Comparative genomics and thermodynamic modeling allow for the prediction and functional characterization of homologous structures in phylogenetically related viruses. We provide here a comprehensive overview of evolutionarily conserved RNAs in the 3′ UTRs of mosquito-borne flaviviruses.

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