How Stats interact with the molecular machinery of transcriptional activation

Thomas Decker, Amanda Jamieson, Matthias Farlik

Veröffentlichungen: Beitrag in BuchBeitrag in Buch/Sammelband


The main purpose of Jak-Stat signal transduction is to adjust the fraction of genes expressed in a genome to environmental cues. The focus of this review is to summarize current knowledge and hypotheses concerning the molecular players and mechanisms that allow Stats to regulate gene expression. We pay particular attention not only to modifications of the Stats themselves, but also to interaction partners with relevance to the remodeling or modification of chromatin or to the recruitment of proteins required for transcriptional initiation and elongation.
TitelJak-Stat Signaling
UntertitelFrom Basics to Disease
Redakteure*innen T. Decker, M. Müller
Herausgeber (Verlag)Springer
PublikationsstatusVeröffentlicht - 2012

ÖFOS 2012

  • 106022 Mikrobiologie


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