@article{04e124d92b1d4a1ab24e9966b6b00c0f,
title = "Inhibition of ABCB1 and ABCG2 at the Mouse Blood-Brain Barrier with Marketed Drugs To Improve Brain Delivery of the Model ABCB1/ABCG2 Substrate [11C]erlotinib",
keywords = "ATP Binding Cassette Transporter, Subfamily B, Member 1/antagonists & inhibitors, ATP Binding Cassette Transporter, Subfamily G, Member 2/antagonists & inhibitors, Animals, Blood-Brain Barrier/metabolism, Brain/metabolism, Capillary Permeability/physiology, Cyclosporine/administration & dosage, Drug Interactions, Erlotinib Hydrochloride/administration & dosage, Female, Mice, Models, Animal, Positron-Emission Tomography/methods, Protein Kinase Inhibitors/administration & dosage, Quinolines/administration & dosage, Radiopharmaceuticals/administration & dosage, Solubility, Tissue Distribution, P-GLYCOPROTEIN, tyrosine kinase inhibitors, IN-VITRO, ERLOTINIB, CANCER RESISTANCE PROTEIN, blood-brain barrier, breast cancer resistance protein, [C-11]erlotinib, PENETRATION, SUBFAMILY-B MEMBER-1, P-glycoprotein, EFFLUX, TRANSPORT ACTIVITY, positron emission tomography, REVERSES MULTIDRUG-RESISTANCE, PET, [ C]erlotinib",
author = "Alexander Traxl and Severin Mairinger and Thomas Filip and Michael Sauberer and Johann Stanek and Stefan Poschner and Walter J{\"a}ger and Viktoria Zoufal and Gaia Novarino and Nicolas Tournier and Martin Bauer and Thomas Wanek and Oliver Langer",
note = "Publisher Copyright: {\textcopyright} 2019 American Chemical Society.",
year = "2019",
month = mar,
day = "4",
doi = "10.1021/acs.molpharmaceut.8b01217",
language = "English",
volume = "16",
pages = "1282--1293",
journal = "Molecular Pharmaceutics",
issn = "1543-8384",
publisher = "AMER CHEMICAL SOC",
number = "3",
}
