Investigations into the Chemistry and Insecticidal Activity of Euonymus europaeus Seed Oil and Methanol Extract

Jürgen Wanner (Korresp. Autor*in), Nurhayat Tabanca, Martin Zehl, Leopold Jirovetz, Erich Schmidt, Andreas Patschka, Abbas Ali, Alden S. Estep, James J. Becnel, Andrew Y. Li, Ikhlas A. Khan

    Veröffentlichungen: Beitrag in FachzeitschriftArtikelPeer Reviewed


    Euonymus europaeus seeds and seed oil were investigated for their volatiles using GC-MS-FID and Headspace- SPME/GC-MS-FID, and for their non-volatile compounds using derivative GC-MS-FID and HPLC-DAD-CAD/MS. The seeds contain about 30% of fatty oil, mainly glyceryl trioleate, small amounts of abietadiene and -triene, dihydroagarofurane sesquiterpenes, and alkaloids of the sesquiterpene pyridine type. Breakdown products of the latter can be found by transesterification with tetramethylammonium hydroxide. In the seed oil, glyceryl acetates are slowly formed through cleavage of alkaloids and triglycerides. Bioassay results indicated both the seed oil and methanol extract had weak repellent and larvicidal activity against the yellow fever mosquito (Aedes aegypti), and were ineffective in repelling the long star tick (Amblyomma americanum) at the concentrations tested.
    Seiten (von - bis)13 - 22
    FachzeitschriftCurrent Bioactive Compounds
    PublikationsstatusVeröffentlicht - 2015

    ÖFOS 2012

    • 301212 Klinische Pharmazie
    • 301204 Pharmakognosie
    • 301207 Pharmazeutische Chemie