Meropenem Population Pharmacokinetics and Simulations in Plasma, Cerebrospinal Fluid, and Brain Tissue

Mohammad H Alshaer; Brooke Barlow; Nicole Maranchick; Miriam Moser; Leon Gramss; Heinz Burgmann; Valentin Al Jalali; Michael Wölfl-Duchek; Walter Jäger; Stefan Poschner; Walter Plöchl; Andrea Reinprecht; Karl Rössler; Andreas Gruber; Markus Zeitlinger; Charles A Peloquin; Arthur Hosmann

doi:10.1128/aac.00438-22

Meropenem Population Pharmacokinetics and Simulations in Plasma, Cerebrospinal Fluid, and Brain Tissue

Mohammad H Alshaer, Brooke Barlow, Nicole Maranchick, Miriam Moser, Leon Gramss, Heinz Burgmann, Valentin Al Jalali, Michael Wölfl-Duchek, Walter Jäger, Stefan Poschner, Walter Plöchl, Andrea Reinprecht, Karl Rössler, Andreas Gruber, Markus Zeitlinger, Charles A Peloquin, Arthur Hosmann

Department für Pharmazeutische Wissenschaften

Veröffentlichungen: Beitrag in Fachzeitschrift › Artikel › Peer Reviewed

Originalsprache	Englisch
Aufsatznummer	e0043822
Seitenumfang	9
Fachzeitschrift	Antimicrobial Agents and Chemotherapy
Jahrgang	66
Ausgabenummer	8
DOIs	https://doi.org/10.1128/aac.00438-22
Publikationsstatus	Veröffentlicht - 16 Aug. 2022

ÖFOS 2012

301205 Pharmakokinetik

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10.1128/aac.00438-22

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Alshaer, M. H., Barlow, B., Maranchick, N., Moser, M., Gramss, L., Burgmann, H., Jalali, V. A., Wölfl-Duchek, M., Jäger, W., Poschner, S., Plöchl, W., Reinprecht, A., Rössler, K., Gruber, A., Zeitlinger, M., Peloquin, C. A., & Hosmann, A. (2022). Meropenem Population Pharmacokinetics and Simulations in Plasma, Cerebrospinal Fluid, and Brain Tissue. Antimicrobial Agents and Chemotherapy, 66(8), Artikel e0043822. https://doi.org/10.1128/aac.00438-22

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title = "Meropenem Population Pharmacokinetics and Simulations in Plasma, Cerebrospinal Fluid, and Brain Tissue",

keywords = "Anti-Bacterial Agents/pharmacokinetics, Brain, Critical Illness, Humans, Meropenem/pharmacokinetics, Monte Carlo Method, Prospective Studies, Thienamycins/pharmacokinetics, central nervous system infections, pharmacodynamics, meropenem, pharmacokinetics, Monte Carlo simulation, CLEARANCE, BARRIER, PENETRATION, MENINGITIS, DRUG TRANSPORT",

author = "Alshaer, {Mohammad H} and Brooke Barlow and Nicole Maranchick and Miriam Moser and Leon Gramss and Heinz Burgmann and Jalali, {Valentin Al} and Michael W{\"o}lfl-Duchek and Walter J{\"a}ger and Stefan Poschner and Walter Pl{\"o}chl and Andrea Reinprecht and Karl R{\"o}ssler and Andreas Gruber and Markus Zeitlinger and Peloquin, {Charles A} and Arthur Hosmann",

year = "2022",

month = aug,

day = "16",

doi = "10.1128/aac.00438-22",

language = "English",

volume = "66",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "AMER SOC MICROBIOLOGY",

number = "8",

}

Alshaer, MH, Barlow, B, Maranchick, N, Moser, M, Gramss, L, Burgmann, H, Jalali, VA, Wölfl-Duchek, M, Jäger, W , Poschner, S, Plöchl, W, Reinprecht, A, Rössler, K, Gruber, A, Zeitlinger, M, Peloquin, CA & Hosmann, A 2022, 'Meropenem Population Pharmacokinetics and Simulations in Plasma, Cerebrospinal Fluid, and Brain Tissue', Antimicrobial Agents and Chemotherapy, Jg. 66, Nr. 8, e0043822. https://doi.org/10.1128/aac.00438-22

TY - JOUR

T1 - Meropenem Population Pharmacokinetics and Simulations in Plasma, Cerebrospinal Fluid, and Brain Tissue

AU - Alshaer, Mohammad H

AU - Barlow, Brooke

AU - Maranchick, Nicole

AU - Moser, Miriam

AU - Gramss, Leon

AU - Burgmann, Heinz

AU - Jalali, Valentin Al

AU - Wölfl-Duchek, Michael

AU - Jäger, Walter

AU - Poschner, Stefan

AU - Plöchl, Walter

AU - Reinprecht, Andrea

AU - Rössler, Karl

AU - Gruber, Andreas

AU - Zeitlinger, Markus

AU - Peloquin, Charles A

AU - Hosmann, Arthur

PY - 2022/8/16

Y1 - 2022/8/16

KW - Anti-Bacterial Agents/pharmacokinetics

KW - Brain

KW - Critical Illness

KW - Humans

KW - Meropenem/pharmacokinetics

KW - Monte Carlo Method

KW - Prospective Studies

KW - Thienamycins/pharmacokinetics

KW - central nervous system infections

KW - pharmacodynamics

KW - meropenem

KW - pharmacokinetics

KW - Monte Carlo simulation

KW - CLEARANCE

KW - BARRIER

KW - PENETRATION

KW - MENINGITIS

KW - DRUG TRANSPORT

UR - http://www.scopus.com/inward/record.url?scp=85136188751&partnerID=8YFLogxK

U2 - 10.1128/aac.00438-22

DO - 10.1128/aac.00438-22

M3 - Article

C2 - 35862739

SN - 0066-4804

VL - 66

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 8

M1 - e0043822

ER -

Meropenem Population Pharmacokinetics and Simulations in Plasma, Cerebrospinal Fluid, and Brain Tissue

ÖFOS 2012

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