TY - JOUR
T1 - Novel screening test to assess the potential environmental toxicity of waste water samples
AU - Fuerhacker, Maria
AU - Lemmens, Rosa
AU - Studenik, Christian
N1 - Zeitschrift: Environmental Toxicology and Pharmacology
DOI: 10.1016/j.etap.2004.09.007
Coden: ETOPF
Affiliations: Inst. Sanitary Eng. Water Poll. C., Muthgasse 18, A-1190 Vienna, Austria; Dept. of Pharmacology and Toxicology, University of Vienna, Althanstrasse 14, A-1090 Vienna, A.
Adressen: Inst. Sanitary Eng. Water Poll. C.; Muthgasse 18; A-1190 Vienna, Austriaemail: [email protected]
Source-File: DirschHeringViernsteinScopus_iso.csv
Import aus Scopus: 2-s2.0-10044261934Zeitschrift: Environmental Toxicology and Pharmacology
DOI: 10.1016/j.etap.2004.09.007
Coden: ETOPF
Affiliations: Inst. Sanitary Eng. Water Poll. C., Muthgasse 18, A-1190 Vienna, Austria; Dept. of Pharmacology and Toxicology, University of Vienna, Althanstrasse 14, A-1090 Vienna, A.
Adressen: Inst. Sanitary Eng. Water Poll. C.; Muthgasse 18; A-1190 Vienna, Austriaemail: [email protected]
Source-File: DirschHeringViernsteinScopus_iso.csv
Import aus Scopus: 2-s2.0-10044261934
Importdatum: 29.11.2006 12:35:33
09.08.2007: Datenanforderung 1812 (Import Sachbearbeiter)
PY - 2005
Y1 - 2005
N2 - Biological effects of waste water samples were investigated using the method for isometric contraction measurements that is widely employed in the medical field for studying the effects of various drugs on heart and smooth muscle preparations. Raw waste water samples from a municipal treatment plant were extracted with chloroform and diluted in dimethylsulfoxide. Some samples were also digested with NaOH or microwave. Our results show that the test is sensitive for the investigation of waste water samples. The liquid part of the samples exerted a more potent relaxing effect on terminal ilea than the solids. Alkaline (NaOH) or microwave treated samples showed similar effects as untreated samples. Therefore we conclude that the major part of the reactive agent might be located in the liquid phase. We also demonstrate with this study that the used method enables the screening of waste water samples and their effect on terminal ilea. This method might be a tool to assess the environmental relevance of complex environmental samples. Π2004 Elsevier B.V. All rights reserved.
AB - Biological effects of waste water samples were investigated using the method for isometric contraction measurements that is widely employed in the medical field for studying the effects of various drugs on heart and smooth muscle preparations. Raw waste water samples from a municipal treatment plant were extracted with chloroform and diluted in dimethylsulfoxide. Some samples were also digested with NaOH or microwave. Our results show that the test is sensitive for the investigation of waste water samples. The liquid part of the samples exerted a more potent relaxing effect on terminal ilea than the solids. Alkaline (NaOH) or microwave treated samples showed similar effects as untreated samples. Therefore we conclude that the major part of the reactive agent might be located in the liquid phase. We also demonstrate with this study that the used method enables the screening of waste water samples and their effect on terminal ilea. This method might be a tool to assess the environmental relevance of complex environmental samples. Π2004 Elsevier B.V. All rights reserved.
M3 - Article
VL - 19
SP - 385
EP - 388
JO - Environmental Toxicology and Pharmacology
JF - Environmental Toxicology and Pharmacology
SN - 1382-6689
IS - 2
ER -
