Rekonstruktion mikrobieller Evolution durch Sequenzierung alter DNA

The study of human pathogens, their genomes and their evolution has been revolutionized by the introduction of ancient DNA techniques both in the lab and in silico. Today, palaeogenomic research can reconstruct microbial genomes starting from as much as a couple of reads detected during screenings. With every year, the number of organisms and genomes increases, and with it the field’s power to answer a wide range of questions pertaining to the evolution and the dynamics of studied pathogens.