Secundarellone A, B, and C from the leaves of Justicia secunda VAHL

Barbara Theiler, Silvia Revoltella, Martin Zehl, Christina Dangl, Lugardo O Espinoza Caisa, Jürgen König, Johannes Winkler, Ernst Urban, Sabine Glasl

Veröffentlichungen: Beitrag in FachzeitschriftArtikelPeer Reviewed

Abstract

The extract of the leaves of Justicia secunda VAHL (Acanthaceae) was subjected to column chromatography on Sephadex LH-20, silica gel, and RP-18e to yield a pure substance (1) and an equimolar mixture of diastereomers (2 and 3). MS and extensive NMR measurements led to the structure elucidation of these new N-arylpyrrolidones as 3-hydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (1), cis-3,5-dihydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (2), and trans-3,5-dihydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (3). They are named secundarellone A (1), B (2) and C (3) and are the first pyrrolidones isolated from the family of Acanthaceae.

OriginalspracheEnglisch
Seiten (von - bis)cxxix–cxxxii
Seitenumfang4
FachzeitschriftPhytochemistry Letters
Jahrgang10
Frühes Online-Datum28 Mai 2014
DOIs
PublikationsstatusVeröffentlicht - Dez. 2014

ÖFOS 2012

  • 301204 Pharmakognosie
  • 301207 Pharmazeutische Chemie
  • 303009 Ernährungswissenschaften

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