TY - JOUR
T1 - Secundarellone A, B, and C from the leaves of Justicia secunda VAHL
AU - Theiler, Barbara
AU - Revoltella, Silvia
AU - Zehl, Martin
AU - Dangl, Christina
AU - Caisa, Lugardo O Espinoza
AU - König, Jürgen
AU - Winkler, Johannes
AU - Urban, Ernst
AU - Glasl, Sabine
PY - 2014/12
Y1 - 2014/12
N2 - The extract of the leaves of Justicia secunda VAHL (Acanthaceae) was subjected to column chromatography on Sephadex LH-20, silica gel, and RP-18e to yield a pure substance (1) and an equimolar mixture of diastereomers (2 and 3). MS and extensive NMR measurements led to the structure elucidation of these new N-arylpyrrolidones as 3-hydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (1), cis-3,5-dihydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (2), and trans-3,5-dihydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (3). They are named secundarellone A (1), B (2) and C (3) and are the first pyrrolidones isolated from the family of Acanthaceae.
AB - The extract of the leaves of Justicia secunda VAHL (Acanthaceae) was subjected to column chromatography on Sephadex LH-20, silica gel, and RP-18e to yield a pure substance (1) and an equimolar mixture of diastereomers (2 and 3). MS and extensive NMR measurements led to the structure elucidation of these new N-arylpyrrolidones as 3-hydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (1), cis-3,5-dihydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (2), and trans-3,5-dihydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (3). They are named secundarellone A (1), B (2) and C (3) and are the first pyrrolidones isolated from the family of Acanthaceae.
KW - Acanthaceae
KW - Justicia secunda VAHL
KW - N-Arylpyrrolidones
KW - Secundarellone
KW - Structure elucidation
UR - http://www.scopus.com/inward/record.url?scp=84910622790&partnerID=8YFLogxK
U2 - 10.1016/j.phytol.2014.05.007
DO - 10.1016/j.phytol.2014.05.007
M3 - Article
AN - SCOPUS:84910622790
SN - 1874-3900
VL - 10
SP - cxxix–cxxxii
JO - Phytochemistry Letters
JF - Phytochemistry Letters
ER -