Size-independent symmetric division in extraordinarily long cells

Nika Pende, Nikolaus Leisch, Harald R. Gruber-Vodicka, Niels R. Heindl, Joerg Ott, Tanneke den Blaauwen, Silvia Bulgheresi (Korresp. Autor*in)

Veröffentlichungen: Beitrag in FachzeitschriftArtikelPeer Reviewed

Abstract

Two long-standing paradigms in biology are that cells belonging to the same population exhibit little deviation from their average size and that symmetric cell division is size limited. Here, ultrastructural, morphometric and immunocytochemical analyses reveal that two Gammaproteobacteria attached to the cuticle of the marine nematodes Eubostrichus fertilis and E. dianeae reproduce by constricting a single FtsZ ring at midcell despite being 45 €‰ 1/4m and 120 €‰ 1/4m long, respectively. In the crescent-shaped bacteria coating E. fertilis, symmetric FtsZ-based fission occurs in cells with lengths spanning one order of magnitude. In the E. dianeae symbiont, formation of a single functional FtsZ ring makes this the longest unicellular organism in which symmetric division has ever been observed. In conclusion, the reproduction modes of two extraordinarily long bacterial cells indicate that size is not the primary trigger of division and that yet unknown mechanisms time the localization of both DNA and the septum.

OriginalspracheEnglisch
Aufsatznummer4803
Seitenumfang10
FachzeitschriftNature Communications
Jahrgang5
DOIs
PublikationsstatusVeröffentlicht - 15 Sep. 2014

ÖFOS 2012

  • 106052 Zellbiologie
  • 106022 Mikrobiologie

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