Projekte pro Jahr
Abstract
Microbial dissimilatory sulfur metabolism utilizing dissimilatory sulfite reductases (Dsr) influenced the biochemical sulfur cycle during Earth’s history and the Dsr pathway is thought to be an ancient metabolic process. Here we performed comparative genomics, phylogenetic, and synteny analyses of several Dsr proteins involved in or associated with the Dsr pathway across over 195,000 prokaryotic metagenomes. The results point to an archaeal origin of the minimal DsrABCMK(N) protein set, having as primordial function sulfite reduction. The acquisition of additional Dsr proteins (DsrJOPT) increased the Dsr pathway complexity. Archaeoglobus would originally possess the archaeal-type Dsr pathway and the archaeal DsrAB proteins were replaced with the bacterial reductive-type version, possibly at the same time as the acquisition of the QmoABC and DsrD proteins. Further inventions of two Qmo complex types, which are more spread than previously thought, allowed microorganisms to use sulfate as electron acceptor. The ability to use the Dsr pathway for sulfur oxidation evolved at least twice, with Chlorobi and Proteobacteria being extant descendants of these two independent adaptations.
Originalsprache | Englisch |
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Seiten (von - bis) | 1680-1692 |
Seitenumfang | 13 |
Fachzeitschrift | The ISME Journal |
Jahrgang | 17 |
Ausgabenummer | 10 |
Frühes Online-Datum | 19 Juli 2023 |
DOIs | |
Publikationsstatus | Veröffentlicht - Okt. 2023 |
ÖFOS 2012
- 106014 Genomik
Projekte
- 2 Laufend
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EvolPhysiol: Evolution of Physiology: The link between Earth and Life
Baltazar de Lima de Sousa, M. F., Jandl, N., van Ham, J., Nascimento Lemos, L., Hilts, A., Naumann, U., Karavaeva, V., Neukirchen, S., Iziumova, I., Ponce Toledo, R. I., Zamarreno Beas, J., Ivesic, C., Leitgeb, C. & Rodrigues de Oliveira, T.
1/02/19 → 31/01/25
Projekt: Forschungsförderung
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Pan-Metabolic Profiling of Archaea: The Ecology of Genomics
Baltazar de Lima de Sousa, M. F., Jandl, N., Neukirchen, S., Nair, G. M., Pichlhöfer, E., Spiegelhofer, J., Pruckner, C., van Ham, J., Padalko, A., Schleper, C. & Ellis, C.
1/06/16 → 30/09/25
Projekt: Forschungsförderung