The Emergence and Impact of the M1UK Lineage on Invasive Group A Streptococcus Disease in Aotearoa New Zealand

Anna Vesty; Xiaoyun Ren; Prachi Sharma; Natalie Lorenz; Thomas Proft; Allan Hardaker; Christina Straub; Julie Morgan; Audrey Tiong; Anneka Anderson; Rachel H. Webb; Julie Bennett; Philip E. Carter; Nicole J. Moreland

doi:10.1093/ofid/ofae457

The Emergence and Impact of the M1_UK Lineage on Invasive Group A Streptococcus Disease in Aotearoa New Zealand

Anna Vesty, Xiaoyun Ren, Prachi Sharma, Natalie Lorenz, Thomas Proft, Allan Hardaker, Christina Straub (Korresp. Autor*in), Julie Morgan, Audrey Tiong, Anneka Anderson, Rachel H. Webb, Julie Bennett, Philip E. Carter, Nicole J. Moreland (Korresp. Autor*in)

Department für Mikrobiologie und Ökosystemforschung

Veröffentlichungen: Beitrag in Fachzeitschrift › Artikel › Peer Reviewed

Abstract

M1_UK is associated with current surges in invasive infection globally, partly due to increased production of superantigen streptococcal pyrogenic exotoxin A. We show that M1_UK is now the dominant invasive emm1 lineage in Aotearoa New Zealand and is genomically related to community infections, suggesting that measures that effectively prevent group A Streptococcus pharyngitis in children could reduce invasive disease.

Originalsprache	Englisch
Aufsatznummer	ofae457
Seitenumfang	4
Fachzeitschrift	Open Forum Infectious Diseases
Jahrgang	11
Ausgabenummer	8
DOIs	https://doi.org/10.1093/ofid/ofae457
Publikationsstatus	Veröffentlicht - 9 Aug. 2024

ÖFOS 2012

106026 Ökosystemforschung
106022 Mikrobiologie

UN SDGs

Dieser Output leistet einen Beitrag zu folgendem(n) Ziel(en) für nachhaltige Entwicklung

Zugriff auf Dokument

10.1093/ofid/ofae457Lizenz: CC BY-NC-ND 4.0

Andere Dateien und Links

Verknüpfung zur Publikation in Scopus

Zitationsweisen

Vesty, A., Ren, X., Sharma, P., Lorenz, N., Proft, T., Hardaker, A., Straub, C., Morgan, J., Tiong, A., Anderson, A., Webb, R. H., Bennett, J., Carter, P. E., & Moreland, N. J. (2024). The Emergence and Impact of the M1_UK Lineage on Invasive Group A Streptococcus Disease in Aotearoa New Zealand. Open Forum Infectious Diseases, 11(8), Artikel ofae457. https://doi.org/10.1093/ofid/ofae457

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abstract = "M1UK is associated with current surges in invasive infection globally, partly due to increased production of superantigen streptococcal pyrogenic exotoxin A. We show that M1UK is now the dominant invasive emm1 lineage in Aotearoa New Zealand and is genomically related to community infections, suggesting that measures that effectively prevent group A Streptococcus pharyngitis in children could reduce invasive disease.",

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author = "Anna Vesty and Xiaoyun Ren and Prachi Sharma and Natalie Lorenz and Thomas Proft and Allan Hardaker and Christina Straub and Julie Morgan and Audrey Tiong and Anneka Anderson and Webb, {Rachel H.} and Julie Bennett and Carter, {Philip E.} and Moreland, {Nicole J.}",

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AU - Proft, Thomas

AU - Hardaker, Allan

AU - Straub, Christina

AU - Morgan, Julie

AU - Tiong, Audrey

AU - Anderson, Anneka

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AU - Carter, Philip E.

AU - Moreland, Nicole J.

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