Use of activated enol ethers in the synthesis of pyrazoles: Reactions with hydrazine and a study of pyrazole tautomerism

Denisa Tarabová, Stanislava Šoralová, Martin Breza, Marek Fronc, Wolfgang Holzer, Viktor Milata (Korresp. Autor*in)

    Veröffentlichungen: Beitrag in FachzeitschriftArtikelPeer Reviewed

    Abstract

    Activated enol ethers derived from esters or the dinitrile of malonic acid, or from pentane-2,4-dione were treated with hydrazine hydrate. The structures of the obtained products – pyrazoles 5 – were studied with a focus on tautomerism and supramolecular structure. A reverse addition of the reagents led to the isolation of two novel products, namely bis-enehydrazines 6 with an unsymmetrical arrangement of the formally equivalent subunits.
    OriginalspracheEnglisch
    Seiten (von - bis)752-760
    Seitenumfang9
    FachzeitschriftBeilstein Journal of Organic Chemistry
    Jahrgang10
    DOIs
    PublikationsstatusVeröffentlicht - 1 Apr. 2014

    ÖFOS 2012

    • 104015 Organische Chemie

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