A primitive vertebrate model for dental evo-devo

    Activity: Talks and presentationsPoster presentationScience to Science

    Description

    The main vertebrate research models are woefully inadequate for the study of dental development and evolution. The only two with any teeth at all, mouse and zebrafish, hardly carry a tooth row representative of mammals or fishes generally. The paddlefish Polyodon, has many primitive osteichthyan characters, including complete homodont tooth rows, as well as other features that make it an attractive vertebrate model. We are characterizing the early events of paddlefish dental development as a model for the general gnathostome dentition, concentrating on the dentary and maxillary tooth rows. We present a description of the form of the dental laminae and the patterns of the first teeth of each row. Later studies will demonstrate the expression of candidate genes in the positional specification, initiation, and early development of teeth in a primitive tooth row.
    Period2006
    Event titleBritish Societies for Cell and Developmental Biology Joint Annual Spring Meeting
    Event typeConference
    LocationYork, United KingdomShow on map