Department of Chromosome Biology

Publications

Publications per year 1993 2005 2006 2007 2008 2009 2010 2011 2013 2016 2017 2018 2021 2024

• 263 Article
• 15 Review
• 7 Short communication
• 5 Chapter
• 12 More
  • 5 Editorial
  • 2 Correction
  • 1 Paper
  • 1 Meeting abstract/Conference paper
  • 1 Other
  • 1 Patent
  • 1 Working paper

Publications per year

Publications per year

Search results

• 2024

  FilamentID reveals the composition and function of metabolic enzyme polymers during gametogenesis

  Hugener, J., Xu, J., Wettstein, R., Ioannidi, L., Velikov, D., Wollweber, F., Henggeler, A., Matos, J. & Pilhofer, M., 20 Jun 2024, In: Cell. 187, 13, p. 3303-3318.e18 16 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Sororin is an evolutionary conserved antagonist of WAPL

  Prusén Mota, I., Galova, M., Schleiffer, A., Nguyen, T-T., Kovacikova, I., Farias Saad, C., Litos, G., Nishiyama, T., Gregan, J., Peters, J-M. & Schlögelhofer, P., Dec 2024, In: Nature Communications. 15, 1, 18 p., 4729.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Waves of regulated protein expression and phosphorylation rewire the proteome to drive gametogenesis in budding yeast

  Wettstein, R., Hugener, J., Gillet, L., Hernández-Armenta, Y., Henggeler, A., Xu, J., van Gerwen, J., Wollweber, F., Arter, M., Aebersold, R., Beltrao, P., Pilhofer, M. & Matos, J., 8 Jul 2024, In: Developmental Cell. 59, 13, p. 1764-1782.e8

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access
• 2023

  Adaptation to spindle assembly checkpoint inhibition through the selection of specific aneuploidies

  Adell, M. A. Y., Klockner, T. C., Höfler, R., Wallner, L., Schmid, J., Markovic, A., Martyniak, A. & Campbell, C., 1 Mar 2023, In: Genes & Development. 37, 5-6, p. 171-190 20 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Cephalopod-omics: Emerging Fields and Technologies in Cephalopod Biology

  Baden, T., Briseño, J., Coffing, G., Cohen-Bodénès, S., Courtney, A., Dickerson, D., Dölen, G., Fiorito, G., Gestal, C., Gustafson, T., Heath-Heckman, E., Hua, Q., Imperadore, P., Kimbara, R., Król, M., Lajbner, Z., Lichilín, N., Macchi, F., McCoy, M. J., Nishiguchi, M. K., & 24 othersNyholm, S. V., Otjacques, E., Pérez-Ferrer, P. A., Ponte, G., Pungor, J. R., Rogers, T. F., Rosenthal, J. J. C., Rouressol, L., Rubas, N., Sanchez, G., Santos, C. P., Schultz, D. T., Seuntjens, E., Songco-Casey, J. O., Stewart, I. E., Styfhals, R., Tuanapaya, S., Vijayan, N., Weissenbacher, A., Zifcakova, L., Schulz, G., Weertman, W., Simakov, O. & Albertin, C., 1 Dec 2023, In: Integrative and Comparative Biology. 63, 6, p. 1226-1239 14 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Hsp70 and Hsp110 Chaperones Promote Early Steps of Proteasome Assembly

  Matias, A. C., Matos, J., Dohmen, R. J. & Ramos, P. C., Jan 2023, In: Biomolecules. 13, 1, 11.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Meiotic nuclear pore complex remodeling provides key insights into nuclear basket organization

  King, G. A., Wettstein, R., Varberg, J. M., Chetlapalli, K., Walsh, M. E., Gillet, L. C. J., Hernández-Armenta, C., Beltrao, P., Aebersold, R., Jaspersen, S. L., Matos, J. & Ünal, E., 6 Feb 2023, In: The Journal of Cell Biology (JCB). 222, 2, e202204039.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Particle fusion of super-resolution data reveals the unit structure of Nup96 in Nuclear Pore Complex

  Wang, W., Jakobi, A., Wu, Y. L., Ries, J., Stallinga, S. & Rieger, B., Dec 2023, In: Scientific Reports. 13, 1, 13327.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• PlantACT! - how to tackle the climate crisis

  Hirt, H., Al-Babili, S., Almeida-Trapp, M., Martin, A., Aranda, M., Bartels, D., Bennett, M., Blilou, I., Boer, D., Boulouis, A., Bowler, C., Brunel-Muguet, S., Chardon, F., Colcombet, J., Colot, V., Daszkowska-Golec, A., Dinneny, J. R., Field, B., Froehlich, K., Gardener, C. H., & 44 othersGojon, A., Gomès, E., Gomez-Alvarez, E. M., Gutierrez, C., Havaux, M., Hayes, S., Heard, E., Hodges, M., Alghamdi, A. K., Laplaze, L., Lauersen, K. J., Leonhardt, N., Johnson, X., Jones, J., Kollist, H., Kopriva, S., Krapp, A., Masson, M. L-P., McCabe, M. F., Merendino, L., Molina, A., Moreno Ramirez, J. L., Mueller-Roeber, B., Nicolas, M., Nir, I., Orduna, I. O., Pardo, J. M., Reichheld, J-P., Rodriguez, P. L., Rouached, H., Saad, M. M., Schlögelhofer, P., Singh, K. A., De Smet, I., Stanschewski, C., Stra, A., Tester, M., Walsh, C., Weber, A. P. M., Weigel, D., Wigge, P., Wrzaczek, M., Wulff, B. B. H. & Young, I. M., 28 May 2023, In: Trends in Plant Science. 28, 5, p. 537-543 7 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • Solutions 100%
  • Scientists 100%
  • Climate 100%
  • Plant 100%
  • Global Warming 100%

• Synergism of the receptor tyrosine kinase Axl with ErbB receptors mediates resistance to regorafenib in hepatocellular carcinoma

  Breitenecker, K., Hedrich, V., Pupp, F., Chen, D., Řezníčková, E., Ortmayr, G., Huber, H., Weber, G., Balcar, L., Pinter, M. & Mikulits, W., 2023, In: Frontiers in Oncology. 13, 1238883.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• TERRA expression is regulated by the telomere-binding proteins POT-1 and POT-2 in Caenorhabditis elegans

  Manzato, C., Larini, L., Oss Pegorar, C., Dello Stritto, M. R., Jurikova, K., Jantsch, V. & Cusanelli, E., 27 Oct 2023, In: Nucleic Acids Research. 51, 19, p. 10681-10699 19 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

  • Telomere-Binding Protein 100%
  • Telomere Shortening 20%
  • Germ Cell 20%
• 2022

  Aurora B activity is promoted by cooperation between discrete localization sites in budding yeast

  Marsoner, T., Yedavalli, P., Masnovo, C., Fink, S., Schmitzer, K. & Campbell, C., 1 Aug 2022, In: Molecular Biology of the Cell. 33, 9, ar85.

  Publications: Contribution to journal › Article › Peer Reviewed

  • Cooperation 100%
  • Budding Yeast 100%
  • Kinetochore 100%
  • Chromosome 80%
  • Centromere 60%

• Release of CHK-2 from PPM-1.D anchorage schedules meiotic entry

  Baudrimont, A., Paouneskou, D., Mohammad, A., Lichtenberger, R., Blundon, J., Kim, Y., Hartl, M., Falk, S., Schedl, T. & Jantsch, V., 18 Feb 2022, In: Science Advances. 8, 7, 17 p., eabl8861.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• The CDK1-TOPBP1-PLK1 axis regulates the Bloom's syndrome helicase BLM to suppress crossover recombination in somatic cells

  Pogliano, C. B., Ceppi, I., Giovannini, S., Petroulaki, V., Palmer, N., Uliana, F., Gatti, M., Kasaciunaite, K., Freire, R., Seidel, R., Altmeyer, M., Cejka, P. & Matos, J., Feb 2022, In: Science Advances. 8, 5, eabk0221.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• The role of bivalent ions in the regulation of D-loop extension mediated by DMC1 during meiotic recombination

  Altmannova, V., Spirek, M., Orlic, L., Jēkabsons, A., Clarence, T., Henggeler, A., Mlcouskova, J., Chaleil, R. A. G., Matos, J. & Krejci, L., 18 Nov 2022, In: Iscience. 25, 11, 105439.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• The topoisomerase 3 zinc finger domain cooperates with the RMI1 scaffold to promote stable association of the BTR complex to recombination intermediates in the Caenorhabditis elegans germline

  Stritto, M. R. D., Vojtassakova, N., Velkova, M., Hamminger, P., Ulm, P. & Jantsch, V., 10 Jun 2022, In: Nucleic Acids Research. 50, 10, p. 5652-5671 20 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access
• 2021

  ATM controls meiotic DNA double-strand break formation and recombination and affects synaptonemal complex organization in plants

  Kurzbauer, M-T., Janisiw, M. P., Paulin, L. F., Prusén Mota, I., Tomanov, K., Krsicka, O., Haeseler, A. V., Schubert, V. & Schlögelhofer, P., May 2021, In: The Plant Cell. 33, 5, p. 1633–1656 24 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Caenorhabditis elegans RMI2 functional homolog-2 (RMIF-2) and RMI1 (RMH-1) have both overlapping and distinct meiotic functions within the BTR complex

  Velkova, M., Silva, N., Stritto, M. R. D., Schleiffer, A., Barraud, P., Hartl, M. & Jantsch, V., 12 Jul 2021, In: PLoS Genetics. 17, 7, 32 p., e1009663.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Conservation and divergence of meiotic DNA double strand break forming mechanisms in Arabidopsis thaliana

  Vrielynck, N., Schneider, K., Rodriguez, M., Sims, J., Chambon, A., Hurel, A., De Muyt, A., Ronceret, A., Krsicka, O., Mezard, C., Schlogelhofer, P. & Grelon, M., 27 Sep 2021, In: Nucleic Acids Research. 49, 17, p. 9821-9835 15 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Dna topoisomerase 3 is required for efficient germ cell quality control

  Stritto, M. R. D., Bauer, B., Barraud, P. & Jantsch, V., 7 Jun 2021, In: Journal of Cell Biology. 220, 6, 23 p., e202012057.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Gene Expression Profiling of Pseudomonas aeruginosa Upon Exposure to Colistin and Tobramycin

  Cianciulli Sesso, A., Lilic, B., Amman, F., Wolfinger, M. T., Sonnleitner, E. & Blasi, U., 30 Apr 2021, In: Frontiers in Microbiology. 12, 19 p., 626715.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC

  Appel, L. M., Franke, V., Bruno, M., Grishkovskaya, I., Kasiliauskaite, A., Kaufmann, T., Schoeberl, U. E., Puchinger, M. G., Kostrhon, S., Ebenwaldner, C., Sebesta, M., Beltzung, E., Mechtler, K., Lin, G., Vlasova, A., Leeb, M., Pavri, R., Stark, A., Akalin, A., Stefl, R., & 3 othersBernecky, C., Djinovic-Carugo, K. & Slade, D., 19 Oct 2021, In: Nature Communications. 12, 1, 24 p., 6078.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Repression of a large number of genes requires interplay between homologous recombination and HIRA

  Misova, I., Pitelova, A., Budis, J., Gazdarica, J., Sedlackova, T., Jordakova, A., Benko, Z., Smondrkova, M., Mayerova, N., Pichlerova, K., Strieskova, L., Prevorovsky, M., Gregan, J., Cipak, L., Szemes, T. & Polakova, S. B., 26 Feb 2021, In: Nucleic Acids Research. 49, 4, p. 1914-1934 21 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Sequencing of the Arabidopsis NOR2 reveals its distinct organization and tissue-specific rRNA ribosomal variants

  Sims, J., Sestini, G., Elgert, C., von Haeseler, A. & Schlögelhofer, P., 15 Jan 2021, In: Nature Communications. 12, 1, 13 p., 387.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Spo11 generates gaps through concerted cuts at sites of topological stress

  Prieler, S., Chen, D., Huang, L., Mayrhofer, E., Zsoter, S., Vesely, M., Mbogning, J. & Klein, F., 24 Jun 2021, In: Nature. 594, p. 577-582 6 p.

  Publications: Contribution to journal › Article › Peer Reviewed

• The cdc14 phosphatase controls resolution of recombination intermediates and crossover formation during meiosis

  Alonso-Ramos, P., Álvarez-Melo, D., Strouhalova, K., Pascual-Silva, C., Garside, G. B., Arter, M., Bermejo, T., Grigaitis, R., Wettstein, R., Fernández-Díaz, M., Matos, J., Geymonat, M., San-Segundo, P. A. & Carballo, J. A., Sep 2021, In: International Journal of Molecular Sciences. 22, 18, 26 p., 9811.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access
• 2020

  A-to-I RNA Editing Uncovers Hidden Signals of Adaptive Genome Evolution in Animals

  Popitsch, N., Huber, C. D., Buchumenski, I., Eisenberg, E., Jantsch, M., von Haeseler, A. & Gallach, M., 1 Apr 2020, In: Genome Biology and Evolution. 12, 4, p. 345-357 13 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Conformation of sister chromatids in the replicated human genome

  Mitter, M., Gasser, C., Takacs, Z., Langer, C. C. H., Tang, W., Jessberger, G., Beales, C. T., Neuner, E., Ameres, S. L., Peters, J-M., Goloborodko, A., Micura, R. & Gerlich, D. W., 1 Oct 2020, In: Nature. 586, 7827, p. 139-144 6 p.

  Publications: Contribution to journal › Article › Peer Reviewed

• Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation

  Sanchez, A., Adam, C., Rauh, F., Duroc, Y., Ranjha, L., Lombard, B., Mu, X., Wintrebert, M., Loew, D., Guarné, A., Gnan, S., Chen, C-L., Keeney, S., Cejka, P., Guérois, R., Klein, F., Charbonnier, J-B. & Borde, V., 1 Dec 2020, In: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 117, 48, p. 30577-30588 12 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• PLK-1 promotes the merger of the parental genome into a single nucleus by triggering lamina disassembly

  Velez-Aguilera, G., Nkombo Nkoula, S., Ossareh-Nazari, B., Link, J., Paouneskou, D., Van Hove, L., Joly, N., Tavernier, N., Verbavatz, J-M., Jantsch, V. & Pintard, L., 8 Oct 2020, In: eLife. 9, 31 p., e59510.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity

  Janisiw, E., Raices, M., Balmir, F., Paulin, L. F., Baudrimont, A., von Haeseler, A., Yanowitz, J. L., Jantsch, V. & Silva, N., 25 Sep 2020, In: Nature Communications. 11, 1, 15 p., 4869.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• RNA polymerase II-binding aptamers in human ACRO1 satellites disrupt transcription in cis

  Boots, J. L., von Pelchrzim, F., Weiss, A., Zimmermann, B., Friesacher, T., Radtke, M., Żywicki, M., Chen, D., Matylla-Kulińska, K., Zagrovic, B. & Schroeder, R., 2020, In: Transcription. 11, 5, p. 217-229 13 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Spatial constraints on chromosomes are instrumental to meiotic pairing

  Tian, M., Agreiter, C. & Loidl, J., 30 Nov 2020, In: Journal of Cell Science. 133, 22, 9 p., jcs253724.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• The Arabidopsis Cdk1/Cdk2 homolog CDKA;1 controls chromosome axis assembly during plant meiosis

  Yang, C., Sofroni, K., Wijnker, E., Hamamura, Y., Carstens, L., Harashima, H., Stolze, S. C., Vezon, D., Chelysheva, L., Orban-Nemeth, Z., Pochon, G., Nakagami, H., Schloegelhofer, P., Grelon, M. & Schnittger, A., 3 Feb 2020, In: EMBO Journal. 39, 3, 19 p., e101625.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• "The nuclear envelope, a meiotic jack-of-all-trades"

  Zetka, M., Paouneskou, D. & Jantsch, V., Jun 2020, In: Current Opinion in Cell Biology. 64, p. 34-42 9 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• The Transmembrane Protein Semi1 Positions Gamete Nuclei for Reciprocal Fertilization in Tetrahymena

  Akematsu, T., Sánchez-Fernández, R., Kosta, F., Holzer, E. & Loidl, J., 24 Jan 2020, In: Iscience. 23, 1, p. 100749 25 p., 100749.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access
• 2019

  A specialized condensin complex participates in somatic nuclear maturation in Tetrahymena thermophila

  Howard-Till, R., Tian, M. & Loidl, J., 14 May 2019, In: Molecular Biology of the Cell. 30, 11, p. 1326-1338 13 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Homologous pairing activities of Arabidopsis thaliana RAD51 and DMC1

  Kobiayashi, W., Liu, E., Ishii, H., Matsunaga, S., Schlögelhofer, P. & Kurumizaka, H., Mar 2019, In: Journal of Biochemistry. 165, 3, p. 289–295 7 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • RAD51 100%
  • Arabidopsis thaliana 100%
  • Homologous Recombination 42%
  • Protein 28%
  • Plant 14%

• Inosine induces context-dependent recoding and translational stalling

  Licht, K., Hartl, M., Amman, F., Anrather, D., Janisiw, M. P. & Jantsch, M. F., 10 Jan 2019, In: Nucleic Acids Research. 47, 1, p. 3-14 12 p., gky1163.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

  • Inosine 100%
  • RNA 30%
  • Adenosine 30%
  • Ribosome 30%
  • Guanosine 20%

• Meiotic chromosome movement: what's lamin got to do with it?

  Paouneskou, D. & Jantsch, V., 30 Jan 2019, In: Nucleus. 10, 1, p. 1-6 6 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Meiotic DNA Repair in the Nucleolus Employs a Nonhomologous End-Joining Mechanism

  Sims, J., Copenhaver, G. P. & Schlögelhofer, P., Sep 2019, In: The Plant Cell. 31, 9, p. 2259-2275 17 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

  • DNA Repair 100%
  • Nucleolus 100%
  • Non-Homologous End Joining 100%
  • Meiosis 100%
  • Homologous Recombination 50%

• Non-coding RNA Transcription in Tetrahymena Meiotic Nuclei Requires Dedicated Mediator Complex-Associated Proteins

  Tian, M., Mochizuki, K. & Loidl, J., 22 Jul 2019, In: Current Biology. 29, 14, p. 2359-2370.e5

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality

  Szmyd, R., Niska-Blakie, J., Diril, M. K., Renck Nunes, P., Tzelepis, K., Lacroix, A., van Hul, N., Deng, L-W., Matos, J., Dreesen, O., Bisteau, X. & Kaldis, P., 6 Sep 2019, In: Oncogene: including Oncogene Reviews. 38, 7, p. 998-1018 21 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Source apportionment of circum-Arctic atmospheric black carbon from isotopes and modeling

  Winiger, P., Barrett, T. E., Sheesley, R. J., Huang, L., Sharma, S., Barrie, L. A., Yttri, K. E., Evangeliou, N., Eckhardt, S., Stohl, A., Klimont, Z., Heyes, C., Semiletov, I. P., Dudarev, O. V., Charkin, A., Shakhova, N., Holmstrand, H., Andersson, A. & Gustafsson, 13 Feb 2019, In: Science Advances. 5, 2, eaau8052.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access
• 2018

  Accurate mapping of tRNA reads

  Hoffmann, A., Fallmann, J., Vilardo, E., Mörl, M., Stadler, P. F. & Amman, F., 1 Apr 2018, In: Bioinformatics. 34, 7, p. 1116-1124 9 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• A chromatin-associated protein required for inducing and limiting meiotic DNA double-strand break formation

  Tian, M. & Loidl, J., 2018, In: Nucleic Acids Research. 46, 22, p. 11822-11834 13 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Arabidopsis thaliana FANCD2 Promotes Meiotic Crossover Formation

  Kurzbauer, M-T., Pradillo, M., Kerzendorfer, C., Sims, J., Ladurner, R., Oliver, C., Janisiw, M. P., Mosiolek, M., Schweizer, D., Copenhaver, G. P. & Schloegelhofer, P., Feb 2018, In: The Plant Cell. 30, 2, p. 415-428 14 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• A streamlined cohesin apparatus is sufficient for mitosis and meiosis in the protist Tetrahymena

  Ali, E. I., Loidl, J. & Howard-Till, R. A., Dec 2018, In: Chromosoma: biology of the nucleus. 127, 4, p. 421-435 15 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• BRCA1-BARD1 associate with the synaptonemal complex and pro-crossover factors and influence RAD-51 dynamics during Caenorhabditis elegans meiosis

  Janisiw, E., Dello Stritto, M. R., Jantsch, V. & Silva, N., Nov 2018, In: PLoS Genetics. 14, 11, 30 p., e1007653.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• C. elegans ZHP-4 is required at multiple distinct steps in the formation of crossovers and their transition to segregation competent chiasmata

  Nguyen, H., Labella, S., Silva, N., Jantsch, V. & Zetka, M., Oct 2018, In: PLoS Genetics. 14, 10, 32 p., e1007776.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access