Franz Klein

Publications

Publications per year 2000 2000 2001 2003 2004 2005 2007 2009 2013 2021

• 23 Article
• 6 Contribution to proceedings
• 1 Chapter

Publications per year

Publications per year

Search results

• 2021

  Spo11 generates gaps through concerted cuts at sites of topological stress

  Prieler, S., Chen, D., Huang, L., Mayrhofer, E., Zsoter, S., Vesely, M., Mbogning, J. & Klein, F., 24 Jun 2021, In: Nature. 594, p. 577-582 6 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • Germ Cell 100%
  • Chromosome Segregation 50%
  • DNA Bending 16%
• 2020

  Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation

  Sanchez, A., Adam, C., Rauh, F., Duroc, Y., Ranjha, L., Lombard, B., Mu, X., Wintrebert, M., Loew, D., Guarné, A., Gnan, S., Chen, C-L., Keeney, S., Cejka, P., Guérois, R., Klein, F., Charbonnier, J-B. & Borde, V., 1 Dec 2020, In: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 117, 48, p. 30577-30588 12 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

  • Polo-Like Kinase 100%
  • Polo Kinase 100%
  • Aneuploidy 33%
  • Endonuclease 33%
  • Budding Yeast 33%
• 2018

  Nuclear dynamics of the Set1C subunit Spp1 prepares meiotic recombination sites for break formation

  Karanyi, Z., Halasz, L., Acquaviva, L., Jonas, D., Hetey, S., Boros-Olah, B., Peng, F., Chen, D., Klein, F., Geli, V. & Szekvolgyi, L., Oct 2018, In: Journal of Cell Biology. 217, 10, p. 3398-3415 18 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

  • Dynamics 100%
  • Meiotic Recombination 100%
  • Histone 50%
  • PHD Finger 50%
  • Chromatin Structure 50%
• 2015

  Transcription dynamically patterns the meiotic chromosome-axis interface

  Sun, X., Huang, L., Markowitz, T. E., Blitzblau, H. G., Chen, D., Klein, F. & Hochwagen, A., 10 Aug 2015, In: eLife. 4, e07424.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

  • Transcription 100%
  • Cohesin 75%
  • Binding Protein 25%
  • Budding Yeast 25%
• 2013

  Budding yeast ATM/ATR control meiotic double-strand break (DSB) levels by down-regulating Rec114, an essential component of the DSB-machinery

  Carballo, J. A., Panizza, S., Serrentino, M. E., Johnson, A. L., Geymonat, M., Borde, V., Klein, F. & Cha, R. S., 27 Jun 2013, In: PLoS Genetics. 9, 6, e1003545.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Smc5/6-Mms21 Prevents and Eliminates Inappropriate Recombination Intermediates in Meiosis

  Xaver, M., Huang, L., Chen, D. & Klein, F., 26 Dec 2013, In: PLoS Genetics. 9, 12, e1004067.

  Publications: Contribution to journal › Article › Peer Reviewed

  Open Access

• Ubc9 Sumoylation Controls SUMO Chain Formation and Meiotic Synapsis in Saccharomyces cerevisiae

  Klug, H., Xaver, M., Chaugule, V. K., Koidl, S., Mittler, G., Klein, F. & Pichler, A., 6 Jun 2013, In: Molecular Cell. 50, 5, p. 625-636 12 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • Sumoylation 100%
  • Synapsis 100%
  • baker's yeast 100%
  • Enzyme 42%
  • Complex Formation 14%
• 2011

  Spo11-Accessory Proteins Link Double-Strand Break Sites to the Chromosome Axis in Early Meiotic Recombination

  Panizza, S., Mendoza Parra, M-A., Berlinger, M., Huang, L., Nicolas, A., Shirahige, K. & Klein, F., 2011, In: Cell. 146, 3, p. 372-383 12 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • Meiotic Recombination 100%
  • Spo11 100%
  • Cohesin 33%
  • DNA Sequence 33%
  • Homologous Chromosome 33%
• 2010

  Leptotene/Zygotene Chromosome Movement Via the SUN/KASH Protein Bridge in Caenorhabditis elegans

  Baudrimont, A., Penkner, A., Woglar, A., Machacek, T., Wegrostek, C., Gloggnitzer, J., Fridkin, A., Klein, F., Gruenbaum, Y., Pasierbek, P. & Jantsch, V., 2010, In: PLoS Genetics. 6, 11, p. 1-19 19 p.

  Publications: Contribution to journal › Article › Peer Reviewed
• 2009

  Separation of roles of Zip1 in meiosis revealed in heterozygous mutants of Saccharomyces cerevisiae

  Xaver, M., Klein, F., Klutstein, M., Simchen, G., Zenvirth, D. & Shemesh, R., 2009, In: Molecular Genetics and Genomics: an international journal.

  Publications: Contribution to journal › Article › Peer Reviewed

• Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity

  Hartinger, C., Mendoza Parra, M-A., Größl, M., Egger, A., Eichinger, R., Mangrum, J., Farrell, N., Maruszak, M., Bednarski, P. J., Klein, F., Jakupec, M., Nazarov, A., Severin, K. & Keppler, B., 2009, In: Journal of Medicinal Chemistry. 52, 4, p. 916-925 10 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • Ruthenium Complex 100%
  • Ruthenium 100%
  • Polycyclic Aromatic Hydrocarbon 100%
  • Oxoplatin 66%
  • Platinum 66%
• 2007

  A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene

  Klein, F., Schlögelhofer, P., Pedrosa-Harand, A., Kerzendorfer, C., Sanchez-Moran, E., Akimcheva, S. A. & Novatchkova, M., 2007, In: The EMBO Journal. 26, 24, p. 5061-5070 10 p.

  Publications: Contribution to journal › Article › Peer Reviewed

• Novel roles for selected genes in meiotic DNA processing

  Klein, F., Leach, D. R. F. & Jordan, P. W., 2007, In: PLoS Genetics. 3, 12

  Publications: Contribution to journal › Article › Peer Reviewed

• The Arabidopsis thaliana AtGR1/COM1 gene is essential for DNA repair in meiosis and links human CtIP with the yeast ScCOM1/SAE2 gene

  Klein, F., Schlögelhofer, P., Pedrosa-Harand, A., Akimcheva, S. A. & Novatchkova, M., 2007, In: The EMBO Journal.

  Publications: Contribution to journal › Article › Peer Reviewed
• 2005

  Mnd2, an essential antagonist of the anaphase-promoting complex during meiotic prophase

  Penkner, A., Prinz, S., Ferscha, S. & Klein, F., 2005, In: Cell. 120, 6, p. 789-801 13 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • Securin 100%

• The control of Spo11's interaction with meiotic recombination hotspots

  Prieler, S., Penkner, A., Borde, V. & Klein, F., 2005, In: Genes & Development. 19, 2, p. 255-269 15 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • DNA Cleavage 100%
• 2004

  GermOnline, a cross-species community knowledgebase on germ cell differentiation

  Wiederkehr, C., Basavaraj, R., Sarrauste de Menthiere, C., Hermida, L., Koch, R., Schlecht, U., Amon, A., Brachat, S., Breitenbach, M., Briza, P., Caburet, S., Cherry, M., Davis, R., Deutschbauer, A. M., Dickinson, H. G., Dumitrescu, T. P., Fellous, M., Goldman, A., Grootegoed, J. A., Hawley, R. S., & 24 othersIshii, R., Jegou, B., Kaufman, R. J., Klein, F., Lamb, N., Maro, B., Nasmyth, K., Nicolas, A., Orr-Weaver, T. L., Philippsen, P., Pineau, C. P., Rabitsch, K. P., Reinke, V., Roest, H. P., Saunders, W. S., Schröder, M., Schedl, T., Siep, M., Villeneuve, A. M., Wolgemuth, D. J., Yamamoto, M., Zickler, D., Esposito, R. E. & Primig, M., 2004, In: Nucleic Acids Research. 32, DATABASE I, p. 560-567 8 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • Germ Line Development 100%
  • Cell Differentiation 100%
  • Germ Cell 100%
  • Reproductive Health 50%
  • Controlled Vocabulary 50%

• Mnd1 is required for meiotic interhomolog repair

  Zierhut, C., Berlinger, M., Rupp, C., Shinohara, A. & Klein, F., 2004, In: Current Biology. 14, 9, p. 752-762 11 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • DNA Template 100%
  • Meiosis 100%
  • Sister Chromatid 66%
  • DNA Repair 66%
  • Homologous Chromosome 66%
• 2001

  A screen for genes required for meiosis and spore formation based on whole-genome expression

  Rabitsch, K. P., Tóth, G., Galova, M., Schleiffer, A., Schaffner, G., Aigner, E., Rupp, C., Penkner, A., Moreno-Borchart, A. C., Primig, M., Esposito, R. E., Klein, F., Knop, M. & Nasmyth, K., 2001, In: Current Biology. 11, 13, p. 1001-1009 9 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • Membrane Formation 100%

• B-type cyclins CLB5 and CLB6 control the initiation of recombination and synaptonemal complex formation in yeast meiosis

  Smith, K. N., Penkner, A., Ohta, K., Klein, F. & Nicolas, A., 2001, In: Current Biology. 11, 2, p. 88-97 10 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • Complex Formation 100%
  • Cyclin 100%
  • Synaptonemal Complex 100%
  • Meiosis 100%
  • DNA Synthesis 80%
• 2000

  HO endonuclease-induced recombination in yeast meiosis resembles Spo11-induced events

  Malkova, A. L., Klein, F., Leung, W. Y. & Haber, J. E., 2000, In: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 97, 26, p. 14500-14505 6 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • Endonuclease 100%
  • Spo11 100%
  • Meiosis 100%
  • Crossing over 75%
  • Mitosis 75%

• How was the reductional division invented? A contribution to the Mendel Centenary Congress

  Klein, F., 2000, In: Vorträge für Pflanzenzüchtung. 48, p. 159-164 6 p.

  Publications: Contribution to journal › Article › Peer Reviewed

• Identification of high affinity Tbf1p binding sites within the budding yeast genome

  Koering, C. E., Fourel, G., Binet-Brasselet, E., Laroche, T., Klein, F. & Gilson, E., 2000, In: Nucleic Acids Research. 28, 13, p. 2519-2526 8 p.

  Publications: Contribution to journal › Article › Peer Reviewed

  • Budding Yeast 100%
  • Binding Site 100%
  • DNA-binding Domain 50%
  • DNA Binding 50%
  • Transactivation 25%