Katharina Pallitsch

2024

Decrypting the function of recurrent ancillary enzymes in bacterial phosphonate catabolism

Ruffolo, F., Zangelmi, E., Dinhof, T., Malatesta, M., Gerdol, M., Chin, J. P., Secchi, A., Rivetti, C., Pallitsch, K. & Peracchi, A., Jun 2024, In: FEBS Open Bio. 14, Supplement: 2, p. 153-154 P-11-003.

Publications: Contribution to journal › Meeting abstract/Conference paper › Peer Reviewed

Development and In Vivo Evaluation of Small-Molecule Ligands for Positron Emission Tomography of Immune Checkpoint Modulation Targeting Programmed Cell Death 1 Ligand 1

Bamminger, K., Pichler, V., Vraka, C., Limberger, T., Moneva, B., Pallitsch, K., Lieder, B., Zacher, A. S., Ponti, S., Benčurová, K., Yang, J., Högler, S., Kodajova, P., Kenner, L., Hacker, M. & Wadsak, W., 14 Mar 2024, In: Journal of Medicinal Chemistry. 67, 5, p. 4036-4062 27 p.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

2023

Asymmetric Transfer Hydrogenation as a Key Step in the Synthesis of the Phosphonic Acid Analogs of Aminocarboxylic Acids

Dinhof, T., Kalina, T., Stanković, T., Braunsteiner, K., Rohrbach, P., Turhan, E., Gradwohl, A., Königshofer, A., Horak, J. & Pallitsch, K., 22 Dec 2023, In: Chemistry - A European Journal. 29, 72, e202302171.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

Deciphering the role of recurrent FAD-dependent enzymes in bacterial phosphonate catabolism

Zangelmi, E., Ruffolo, F., Dinhof, T., Gerdol, M., Malatesta, M., Chin, J. P., Rivetti, C., Secchi, A., Pallitsch, K. & Peracchi, A., 17 Nov 2023, In: Iscience. 26, 11, 108108.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

Fluorinated Analogues to the Pentuloses of the Pentose Phosphate Pathway

Scheibelberger, L., Stankovic, T., Liepert, K., Kienzle, A., Patronas, E. M., Balber, T., Mitterhauser, M., Haschemi, A. & Pallitsch, K., 14 Aug 2023, In: European Journal of Organic Chemistry. 26, 31, e202300339.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

On the Road towards Small-Molecule Programmed Cell Death 1 Ligand 1 Positron Emission Tomography Tracers: A Ligand-Based Drug Design Approach

Bamminger, K., Pichler, V., Vraka, C., Nehring, T., Pallitsch, K., Lieder, B., Hacker, M. & Wadsak, W., Jul 2023, In: Pharmaceuticals. 16, 7, 1051.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

Synthesis of 4-Deoxy-4-Fluoro-D-Sedoheptulose: A Promising New Sugar to Apply the Principle of Metabolic Trapping

Scheibelberger, L., Stankovic, T., Pühringer, M., Kählig, H., Balber, T., Patronas, E. M., Rampler, E., Mitterhauser, M., Haschemi, A. & Pallitsch, K., 8 Nov 2023, In: Chemistry - A European Journal. 29, 62, e202302277.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

The functional importance of bacterial oxidative phosphonate pathways

Pallitsch, K. & Zechel, D. L., Apr 2023, In: Biochemical Society Transactions. 51, 2, p. 487-499 13 p.

Publications: Contribution to journal › Review › Peer Reviewed

The Microbial Degradation of Natural and Anthropogenic Phosphonates

Ruffolo, F., Dinhof, T., Murray, L., Zangelmi, E., Chin, J. P., Pallitsch, K. & Peracchi, A., Oct 2023, In: Molecules. 28, 19, 6863.

Publications: Contribution to journal › Review › Peer Reviewed

Open Access

2022

Biosynthesis of the Fungal Organophosphonate Fosfonochlorin Involves an Iron(II) and 2-(Oxo)glutarate Dependent Oxacyclase

Gama, S. R., Stankovic, T., Hupp, K., Al Hejami, A., McClean, M., Evans, A., Beauchemin, D., Hammerschmidt, F., Pallitsch, K. & Zechel, D. L., 19 Jan 2022, In: ChemBioChem: a european journal of chemical biology. 23, 2, 8 p., e202100352.

Publications: Contribution to journal › Article › Peer Reviewed

2021

As Similar As Possible, As Different As Necessary - On-Site Laboratory Teaching during the COVID-19 Pandemic

Mosiagin, I., Pallitsch, K., Klose, S. I., Preinfalk, A. & Maulide, N., 12 Oct 2021, In: Journal of Chemical Education. 98, 10, p. 3143-3152 10 p.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

Discovery of a New, Recurrent Enzyme in Bacterial Phosphonate Degradation: (R)-1-Hydroxy-2-aminoethylphosphonate Ammonia-lyase

Zangelmi, E., Stankovic, T., Malatesta, M., Acquotti, D., Pallitsch, K. & Peracchi, A., 20 Apr 2021, In: Biochemistry. 60, 15, p. 1214-1225 12 p.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

Discovery of melanin-concentrating hormone receptor 1 in brown adipose tissue

Philippe, C., Klebermass, E-M., Balber, T., Kulterer, O. C., Zeilinger, M., Egger, G., Dumanic, M., Herz, C. T., Kiefer, F. W., Scheuba, C., Scherer, T., Fuernsinn, C., Vraka, C., Pallitsch, K., Spreitzer, H., Wadsak, W., Viernstein, H., Hacker, M. & Mitterhauser, M., Jun 2021, In: Annals of the New York Academy of Sciences. 1494, 1, p. 70-86 17 p.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

Overall Retention of Methyl Stereochemistry during B-12-Dependent Radical SAM Methyl Transfer in Fosfomycin Biosynthesis

McLaughlin, M., Pallitsch, K., Wallner, G., van der Donk, W. A. & Hammerschmidt, F., 25 May 2021, In: Biochemistry. 60, 20, p. 1587-1596 10 p.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

Towards understanding the magnetism of Os(iv) complexes: an ab initio insight

Ungur, L., Pallitsch, K., AlOthman, Z. A., Al-Kahtani, A. A. S., Arion, V. B. & Chibotaru, L. F., Aug 2021, In: Dalton Transactions. 50, 36, p. 12537-12546 10 p.

Publications: Contribution to journal › Article › Peer Reviewed

2019

(R)-[F-18]NEBIFQUINIDE: A promising new PET tracer for TSPO imaging

Berroteran-Infante, N., Kalina, T., Fetty, L., Janisch, V., Velasco, R., Vraka, C., Hacker, M., Haug, A. R., Pallitsch, K., Wadsak, W. & Mitterhauser, M., 15 Aug 2019, In: European Journal of Medicinal Chemistry. 176, p. 410-418 9 p.

Publications: Contribution to journal › Article › Peer Reviewed

An Oxidative Pathway for Microbial Utilization of Methylphosphonic Acid as a Phosphate Source

Gama, S. R., Vogt, M., Kalina, T., Hupp, K., Hammerschmidt, F., Pallitsch, K. & Zechel, D. L., Apr 2019, In: ACS Chemical Biology. 14, 4, p. 735-741 7 p.

Publications: Contribution to journal › Article › Peer Reviewed

C-H Bond Cleavage Is Rate-Limiting for Oxidative C-P Bond Cleavage by the Mixed Valence Diiron-Dependent Oxygenase PhnZ

Gama, S. R., Lo, B. S. Y., Seguin, J., Pallitsch, K., Hammerschmidt, F. & Zechel, D. L., 31 Dec 2019, In: Biochemistry. 58, 52, p. 5271-5280 10 p.

Publications: Contribution to journal › Article › Peer Reviewed

Facilitated troubleshooting in (+)-[C-11]PHNO synthesis by investigation of reagents, byproducts, and intermediates

Pfaff, S., Philippe, C., Nics, L., Berroteran-Infante, N., Pallitsch, K., Rami-Mark, C., Weidenauer, A., Sauerzopf, U., Willeit, M., Mitterhauser, M., Hacker, M., Wadsak, W. & Pichler, V., May 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, p. 255-257 3 p.

Publications: Contribution to journal › Meeting abstract/Conference paper › Peer Reviewed

In vitro Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes

Balber, T., Bencurova, K., Kiefer, F. W., Kulterer, O. C., Klebermass, E-M., Egger, G., Tran, L., Wagner, K-H., Viernstein, H., Pallitsch, K., Spreitzer, H., Hacker, M., Wadsak, W., Mitterhauser, M. & Philippe, C., 11 Jun 2019, In: Frontiers in Endocrinology. 10, 324.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

Optimization of the Automated Synthesis of [ ¹¹C ]mHED—Administered and Apparent Molar Activities

Vraka, C., Pichler, V., Berroterán-Infante, N., Wollenweber, T., Pillinger, A., Hohensinner, M., Fetty, L., Beitzke, D., Li, X., Philippe, C., Pallitsch, K., Mitterhauser, M., Hacker, M. & Wadsak, W., 14 Jan 2019, In: Pharmaceuticals. 12, 1, 14 p., 12.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

SNAPshots of the MCHR1: a Comparison Between the PET-Tracers [F-18]FE@SNAP and [C-11]SNAP-7941

Philippe, C., Zeilinger, M., Dumanic, M., Pichler, F., Fetty, L., Vraka, C., Balber, T., Wadsak, W., Pallitsch, K., Spreitzer, H., Lanzenberger, R., Hacker, M. & Mitterhauser, M., 15 Apr 2019, In: Molecular Imaging and Biology. 21, 2, p. 257-268 12 p.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

Synthesis and in vitro evaluation of new translocator protein ligands designed for positron emission tomography

Kalina, T., Berroterán-Infante, N., Schmitl, S., Vraka, C., Hacker, M., Mitterhauser, M., Pallitsch, K. & Wadsak, W., 1 Mar 2019, In: Future Medicinal Chemistry. 11, 6, p. 539-550 12 p.

Publications: Contribution to journal › Article › Peer Reviewed

Synthetic Phosphonic Acids as Potent Tools to Study Phosphonate Enzymology

Pallitsch, K., Kalina, T. & Stanković, T., Apr 2019, In: Synlett. 30, 7, p. 770-776 7 p.

Publications: Contribution to journal › Article › Peer Reviewed

Toward the Optimization of (+)-[11C]PHNO Synthesis: Time Reduction and Process Validation

Pfaff, S., Philippe, C., Nics, L., Berroteran-Infante, N., Pallitsch, K., Rami-Mark, C., Weidenauer, A., Sauerzopf, U., Willeit, M., Mitterhauser, M., Hacker, M., Wadsak, W. & Pichler, V., 2019, In: Contrast media & molecular imaging. 2019, 13 p., 4292596.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

2018

PcxL and HpxL are flavin-dependent, oxime-forming N-oxidases in phosphonocystoximic acid biosynthesis in Streptomyces

Goettge, M. N., Cioni, J. P., Ju, K-S., Pallitsch, K. & Metcalf, W. W., 4 May 2018, In: Journal of Biological Chemistry. 293, 18, p. 6859-6868 10 p.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

Preclinical in Vitro and in Vivo Evaluation of [ ¹⁸F]FE@SUPPY for Cancer PET Imaging: Limitations of a Xenograft Model for Colorectal Cancer

Balber, T., Singer, J., Berroteran-Infante, N., Dumanic, M., Fetty, L., Fazekas-Singer, J., Vraka, C., Nics, L., Bergmann, M., Pallitsch, K., Spreitzer, H., Wadsak, W., Hacker, M., Jensen-Jarolim, E., Viernstein, H. & Mitterhauser, M., 2018, In: Contrast media & molecular imaging. 2018, 9 p., 1269830.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

2017

Determination of the Absolute Configuration of (-)-Hydroxynitrilaphos and Related Biosynthetic Questions

Pallitsch, K., Happl, B. & Stieger, C., 7 Nov 2017, In: Chemistry: A European Journal. 23, 62, p. 15655-15665 11 p.

Publications: Contribution to journal › Article › Peer Reviewed

In vivo evaluation of radiotracers targeting the melanin-concentrating hormone receptor 1: [ ¹¹C]SNAP-7941 and [ ¹⁸F]FE@SNAP reveal specific uptake in the ventricular system

Zeilinger, M., Dumanic, M., Pichler, F., Budinsky, L., Wadsak, W., Pallitsch, K., Spreitzer, H., Hacker, M., Mitterhauser, M. & Philippe, C., 14 Aug 2017, In: Scientific Reports. 7, 10 p., 8054.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

Phosphonodifluoropyruvate is a mechanism-based inhibitor of phosphonopyruvate decarboxylase from Bacteroides fragilis

Pallitsch, K., Rogers, M. P., Andrews, F. H., Hammerschmidt, F. & McLeish, M. J., 15 Aug 2017, In: Bioorganic & Medicinal Chemistry. 25, 16, p. 4368-4374 7 p.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

Towards the biodegradation pathway of fosfomycin

Pallitsch, K., Schweifer, A., Roller, A. & Hammerschmidt, F., 19 Apr 2017, In: Organic & Biomolecular Chemistry. 15, 15, p. 3276-3285 10 p.

Publications: Contribution to journal › Article › Peer Reviewed

Open Access

2015

The Stereochemical Course of the α-Hydroxyphosphonate-Phosphate Rearrangement

Pallitsch, K., Roller, A. & Hammerschmidt, F., 6 Jul 2015, In: Chemistry: A European Journal. 21, 28, p. 10200-10206 7 p.

Publications: Contribution to journal › Article › Peer Reviewed

2014

Crystal structure of PhnZ in complex with substrate reveals a di-iron oxygenase mechanism for catabolism of organophosphonates

van Staalduinen, L. M., McSorley, F. R., Schiessl, K., Seguin, J., Wyatt, P. B., Hammerschmidt, F., Zechel, D. L. & Jia, Z., 8 Apr 2014, In: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 111, 14, p. 5171-5176 6 p.

Publications: Contribution to journal › Article › Peer Reviewed

Stereochemistry of alpha-Hydroxyphosphonate-Phosphate rearrangement

Pallitsch, K., Roller, A. & Hammerschmidt, F., 28 Jun 2014.

Publications: Contribution to conference › Paper

2013

Determination of absolute configuration of the phosphonic acid moiety of fosfazinomycins

Schiessl, K., Roller, A. & Hammerschmidt, F., 14 Nov 2013, In: Organic & Biomolecular Chemistry. 11, 42, p. 7420-7426 7 p.

Publications: Contribution to journal › Article › Peer Reviewed

On the Electronic Structure of mer,trans-[RuCl3(1H-indazole)2(NO)], a Hypothetical Metabolite of the Antitumor Drug Candidate KP1019: An Experimental and DFT Study

Bucinsky, L., Büchel, G., Ponec, R., Rapta, P., Breza, M., Kozisek, J., Gall, M., Biskupic, S., Fronc, M., Schiessl, K., Cuzan, O., Prodius, D., Turta, C., Shova, S., Zajac, D. A. & Arion, V., 2013, In: European Journal of Inorganic Chemistry. 14, p. 2505-2519 15 p.

Publications: Contribution to journal › Article › Peer Reviewed

Katharina Pallitsch

Publications

Search results