Michael Jakupec

Activities

Activities per year 2004 2006 2007 2008 2010 2014 2023

• 92 Poster presentation
• 29 Talk or oral contribution

Activities per year

Search results

• Novel platinum(IV) complexes with high cytotoxicity

  Hristo Varbanov (Contributor), Seied Mojtaba Valiahdi (Contributor), Galanski, M. S. (Contributor), Michael Jakupec (Contributor), Vladimir Arion (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Influence of arene ligand, metal center and the leaving group on the in vitro anticancer activity of organometallic compounds linked with carbohydrate based ligands

  Alexey Nazarov (Contributor), Christian Hartinger (Contributor), Isabella Berger (Contributor), Michael Jakupec (Contributor), Paul J. Dyson (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Controlling the reactivity of anticancer active organometallic compounds

  Christian Hartinger (Contributor), Alexey Nazarov (Contributor), Isabella Berger (Contributor), Michael Jakupec (Contributor), Paul J. Dyson (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• The influence of electroporation on cytotoxicity of anticancer ruthenium(III) compounds in vitro and in vivo

  Rosana Hudej (Contributor), Maja Cemazar (Contributor), Masa Kanduser (Contributor), Janez Scancar (Contributor), Simona Kranjc (Contributor), Gregor Sersa (Contributor), Damijan Miklavcic (Contributor), Michael Jakupec (Contributor), Bernhard Keppler (Contributor) & Iztok Turel (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Organometallic 3-(1H-benzimidazol-2-yl)-pyrazolo[3,4-b]pyridines: synthesis, structure, spectroscopic characterization, and antiproliferative activity

  Iryna Stepanenko (Contributor), Vladimir Arion (Contributor), Michaela Hejl (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Organometallic ruthenium and osmium complexes with carbohydrate-based ligands as anticancer agents

  Alexey Nazarov (Contributor), Lucienne Juillerat-Jeanneret (Contributor), Christian Hartinger (Contributor), Olivier Zava (Contributor), Michael Jakupec (Contributor), Bernhard Keppler (Contributor) & Paul J. Dyson (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Synthesis, characterization and antiproliferative activity of [OsCl5(Hazole)]- complexes

  Gabriel Büchel (Contributor), Iryna Stepanenko (Contributor), Michaela Hejl (Contributor), Michael Jakupec (Contributor), Vladimir Arion (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Cellular uptake and DNA interaction studies of active trans-platinum anticancer compounds

  Caroline Bartel (Contributor), Yulia Scaffidi-Domianello (Contributor), Kristof Meelich (Contributor), Nikolay Kukushkin (Contributor), Michael Jakupec (Contributor), Vadim Yu Kukushkin (Contributor), Galanski, M. S. (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Metallorganic indolobenzazepines versus indoloquinolines: the impact of ligand planarity on physico-chemical and biological properties

  Lukas Filak (Contributor), Gerhard Mühlgassner (Contributor), Michael Jakupec (Contributor), Vladimir Arion (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Organoruthenium Cdk inhibitors with a chance to be delivered by a carrier protein molecule (rHSA) to cancer cells

  Iryna Stepanenko (Contributor), Vladimir Arion (Contributor), Maria Novak (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Pyrone-derived Ru(II) complexes and their biological activity

  Michael Jakupec (Contributor)

  25 Sept 2009

  Activity: Talks and presentations › Talk or oral contribution › Other

• Subcellular distribution study by means of the inherent fluorescence of the investigational drug Triapine and its zinc(II) complex

  Robert Trondl (Contributor), Christian Kowol (Contributor), Vladimir Arion (Contributor), Michael Jakupec (Contributor), Irene Lichtscheidl-Schultz (Contributor) & Bernhard Keppler (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Other

• Cytotoxic effect of the ruthenium compound KP1339 potentiated by electroporation

  Rosana Hudej (Contributor), Iztok Turel (Contributor), Maja Cemazar (Contributor), Masa Kanduser (Contributor), Simona Kranjc (Contributor), Damijan Miklavcic (Contributor), Gregor Sersa (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Science to Science

• The cytotoxic potential of 4-pyrone and 4-thiopyrone derived Ru(II)-cymene complexes and their behaviour in aqueous solution

  Wolfgang Kandioller (Contributor), Christian Hartinger (Contributor), Alexey Nazarov (Contributor), Roland John (Contributor), Caroline Bartel (Contributor), Matthias Skocic (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Science to Science

• The gallium complex KP46 exerts strong activity against primary explanted melanoma cells and induces apoptosis in melanoma cell lines

  Seied Mojtaba Valiahdi (Contributor), Petra Heffeter (Contributor), Michael Jakupec (Contributor), Rodrig Marculescu (Contributor), Walter Berger (Contributor), Klemens Rappersberger (Contributor) & Bernhard Keppler (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Science to Science

• New insights into the mechanisms underlying the anticancer activity of the gallium compound NKP46: impact of DNA damage

  Ute Jungwirth (Contributor), Petra Heffeter (Contributor), Rita Dornetshuber (Contributor), Seied Mojtaba Valiahdi (Contributor), Michael Jakupec (Contributor), Leonilla Elbling (Contributor), Michael Micksche (Contributor), Bernhard Keppler (Contributor) & Walter Berger (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Science to Science

• The Ga coordination sphere of KP46 in solution and in cancer cells - a XAS investigation

  Annette Rompel (Contributor), Ana Mijovilovich (Contributor), Wolfram Meyer-Klaucke (Contributor), Ladislav Novotny (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Science to Science

• Novel mono-substituted oxaliplatin analogs with improved Characteristics

  Ute Jungwirth (Contributor), Petra Heffeter (Contributor), Michael Jakupec (Contributor), Galanski, M. S. (Contributor), Wilfried Körner (Contributor), Michael Micksche (Contributor), Bernhard Keppler (Contributor) & Walter Berger (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Science to Science

• Metal-based paullones as potential antitumour drugs

  Vladimir Arion (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Science to Science

• Anticancer active RAPTA-C analogues with carbohydrate-based ligands: in vitro anticancer activity and metabolization

  Michael Jakupec (Contributor)

  11 Nov 2008

  Activity: Talks and presentations › Talk or oral contribution › Other

• Structure-activity relationships and DNA platination of new di- and tetracarboxylatoplatinum(IV) complexes

  Michael Jakupec (Contributor)

  19 May 2008

  Activity: Talks and presentations › Talk or oral contribution › Other

• Osmium(II)/(III)-dmso-azole complexes: synthesis, properties and application

  Michael Jakupec (Contributor)

  17 Mar 2008

  Activity: Talks and presentations › Talk or oral contribution › Other

• A new gallium complex exerts strong activity against primary explanted melanoma cells and cell cycle perturbation in metastatic melanoma cell lines

  Seied Mojtaba Valiahdi (Contributor), Michael Jakupec (Contributor), Rodrig Marculescu (Contributor), Walter Berger (Contributor), Klemens Rappersberger (Contributor) & Bernhard Keppler (Contributor)

  2008

  Activity: Talks and presentations › Poster presentation › Science to Science

• Ruthenium-based anticancer agent in combination with electroporation exerts higher cytotoxicity than agent alone

  Ajda Bicek (Contributor), Masa Kanduser (Contributor), Rosana Hudej (Contributor), Damijan Miklavcic (Contributor), Michael Jakupec (Contributor), Bernhard Keppler (Contributor) & Iztok Turel (Contributor)

  2008

  Activity: Talks and presentations › Poster presentation › Science to Science

• Synthesis, structure, spectroscopic properties, and antiproliferative activity in vitro of [OsCl2(azole)4]Cl

  Iryna Stepanenko (Contributor), Artem Krokhin (Contributor), Roland John (Contributor), Vladimir Arion (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2008

  Activity: Talks and presentations › Poster presentation › Science to Science

• Oxidative stress induced expression of angiogenic factors in hepatocellular carcinoma is related to selenium status

  Nataliya Rohr-Udilova (Contributor), Wolfgang Sieghart (Contributor), Klaus Stolze (Contributor), Bernhard Keppler (Contributor), Michael Jakupec (Contributor), Bettina Grasl-Kraupp (Contributor) & Markus Peck-Radosavljevic (Contributor)

  2008

  Activity: Talks and presentations › Poster presentation › Science to Science

• Preclinical Characterisation of Novel Oxaliplatin Analogues

  Ute Jungwirth (Contributor), Petra Heffeter (Contributor), Michael Jakupec (Contributor), Ladislav Habala (Contributor), Alexey Nazarov (Contributor), Mathea Sophia Galanski (Contributor), Wilfried Körner (Contributor), Michael Micksche (Contributor), Bernhard Keppler (Contributor) & Walter Berger (Contributor)

  2008

  Activity: Talks and presentations › Poster presentation › Science to Science

• Metal-based Paullones as potential antitumour drugs

  Vladimir Arion (Contributor), Wolfgang Schmid (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2008

  Activity: Talks and presentations › Poster presentation › Science to Science

• In vitro anticancer activity and biologically-relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands

  Christian Hartinger (Contributor), Alexey Nazarov (Contributor), Isabella Berger (Contributor), Maxim L. Kuznetsov (Contributor), Michael Größl (Contributor), Frederic Schmitt (Contributor), Olivier Zava (Contributor), Michael Jakupec (Contributor), Lucienne Juillerat-Jeanneret (Contributor), Paul J. Dyson (Contributor) & Bernhard Keppler (Contributor)

  2008

  Activity: Talks and presentations › Poster presentation › Science to Science

• Radiosynthesis and quality control of 68Ga@KP46 (68Ga-oxine)

  Johanna Ungersböck (Contributor), Michael Größl (Contributor), Markus Mitterhauser (Contributor), Michael Jakupec (Contributor), Harald Eidherr (Contributor), Peter Unfried (Contributor), Kurt Kletter (Contributor), Robert Dudczak (Contributor), Bernhard Keppler (Contributor) & Wolfgang Wadsak (Contributor)

  2008

  Activity: Talks and presentations › Poster presentation › Science to Science

• Tris(8-quinolinolato)gallium(III) (KP46, FFC11), an investigational anticancer drug in clinical trials

  Michael Jakupec (Invited speaker)

  15 Jul 2007

  Activity: Talks and presentations › Talk or oral contribution › Other

• XAS investigation of the Ga coordination sphere in solution and in cancer cells treated with KP46

  Michael Jakupec (Contributor)

  15 Jul 2007

  Activity: Talks and presentations › Talk or oral contribution › Other

• Novel strategies to develop new antitumor-active metal compounds

  Michael Jakupec (Contributor)

  4 Jul 2007

  Activity: Talks and presentations › Talk or oral contribution › Other

• Wechselwirkung cytotoxischer dinuklearer Ru(II)-Verbindungen mit Biomolekülen

  Michael Jakupec (Contributor)

  1 Jun 2007

  Activity: Talks and presentations › Talk or oral contribution › Other

• Modulating the in vitro activity of dinuclear ruthenium anticancer compounds. surprisingly high cytotoxicity and weak covalent DNA binding ability

  Michael Jakupec (Contributor)

  30 May 2007

  Activity: Talks and presentations › Talk or oral contribution › Other

• A new gallium complex exerts strong activity against primary explanted melanoma cells and cell cycle perturbation in metastatic melanoma cell lines

  Seied Mojtaba Valiahdi (Contributor), Michael Jakupec (Contributor), Rodrig Marculescu (Contributor), Klemens Rappersberger (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• Anticancer activities of new oxaliplatin derivatives

  Ute Jungwirth (Contributor), Petra Heffeter (Contributor), Michael Jakupec (Contributor), Michael Micksche (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• 2,3-Diaminoglucose platinum(II) complexes: synthesis, dGMP binding and cytotoxicity

  Isabella Berger (Contributor), Seied Mojtaba Valiahdi (Contributor), Michael Größl (Contributor), Alexey Nazarov (Contributor), Christian Hartinger (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• Structure-activity relationships for assessing drug-like properties of NAMI-A-type ruthenium(III) complexes

  Michael Größl (Contributor), Erwin Reisner (Contributor), Christian Hartinger (Contributor), Rene Eichinger (Contributor), Olga Semenova (Contributor), Andrei Timerbaev (Contributor), Michael Jakupec (Contributor), Vladimir Arion (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• Synthetic approaches towards new derivatives of the DACH ligand and their utilization in anticancer complexes of platinum

  Ladislav Habala (Contributor), Galanski, M. S. (Contributor), Alexey Nazarov (Contributor), Michael Jakupec (Contributor), Vladimir Arion (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• Influence of extracellular pH on the cytotoxicity of new pH-sensitive cisplatin derivatives

  Seied Mojtaba Valiahdi (Contributor), Kristof Meelich (Contributor), Petra Schluga (Contributor), Michael Jakupec (Contributor), Christian Hartinger (Contributor), Galanski, M. S. (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• Synthesis, structures, spectroscopic and antiproliferative properties of (H2azole)[OsIIICl4(Hazole)(DMSO)]

  Artem Krokhin (Contributor), Berta Cebrian (Contributor), Iryna Stepanenko (Contributor), Rene Eichinger (Contributor), Michael Jakupec (Contributor), Vladimir Arion (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• Synthesis and characterization of substituted 3-hydroxy-4-pyrones and their Ru(II)-arene complexes

  Wolfgang Kandioller (Contributor), Christian Hartinger (Contributor), Alexey Nazarov (Contributor), Roland John (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• [Tris(1,10-phenanthroline)lanthanum(III)] trithiocyanate (KP772, FFC24): a new ribonucleotide reductase inhibitor

  Petra Heffeter (Contributor), Philipp Saiko (Contributor), Michael Jakupec (Contributor), Rita Dornetshuber-Fleiss (Contributor), Leonilla Elbling (Contributor), Hedwig Sutterlüty (Contributor), Michael Micksche (Contributor), Thomas Szekeres (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• Modulating the in vitro anticancer activity of multinuclear ruthenium(II)- and osmium(II)-arene complexes based on pyridinone ligands

  Maria Grazia Mendoza Parra Ferri (Contributor), Marco-Antonio Mendoza Parra (Contributor), Alexander Egger (Contributor), Michael Größl (Contributor), Rene Eichinger (Contributor), Franz Klein (Contributor), Michael Jakupec (Contributor), Christian Hartinger (Contributor), Alexey Nazarov (Contributor), Kay Severin (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• Ribonucleotide reductase inhibition by the new lanthanum compound KP772 (FFC24)

  Petra Heffeter (Contributor), Philipp Saiko (Contributor), Michael Jakupec (Contributor), Michael Micksche (Contributor), Thomas Szekeres (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• Synthesis, hydrolytical stability and biological activity of Ru(II)-arene complexes based on bicyclophosphites of glucofuranosides

  Alexey Nazarov (Contributor), Isabella Berger (Contributor), Florian Biba (Contributor), Christian Hartinger (Contributor), Roland John (Contributor), John Mangrum (Contributor), Galanski, M. S. (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• Osmium(II)- and ruthenium(II)-arene-complexes with oxine ligands and in vitro antitumour activity

  Roland John (Contributor), Raffael Schuecker (Contributor), Vladimir Arion (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• Ruthenium(II) complexes with paullone-based ligands

  Wolfgang Schmid (Contributor), Vladimir Arion (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science

• Synthesis and structure of gallium complexes with paullone derivatives

  Werner Ginzinger (Contributor), Anatolie Dobrov (Contributor), Michael Jakupec (Contributor), Galanski, M. S. (Contributor), Vladimir Arion (Contributor) & Bernhard Keppler (Contributor)

  2007

  Activity: Talks and presentations › Poster presentation › Science to Science