Michael Jakupec

Activities

Activities per year 2004 2006 2007 2008 2010 2014 2023

• 92 Poster presentation
• 29 Talk or oral contribution

Activities per year

Search results

• Smart carriers of a novel theranostic agent for magnetic resonance imaging (MRI)

  Irena Pashkunova-Martic (Contributor), Joachim Friske (Contributor), Michaela Hejl (Contributor), Anton Legin (Contributor), Michael Jakupec (Contributor), Bernhard Keppler (Contributor), Werner Lubitz (Contributor), Thomas H Helbich (Contributor) & Juliana IVANOVA-TOUMBEVA (Contributor)

  14 Mar 2023

  Activity: Talks and presentations › Poster presentation › Science to Science

• Biomimetic bacterial-derived transport vehicles of novel salinomycin-based theranostic probe for magnetic resonance imaging (MRI)

  Irena Pashkunova-Martic (Contributor), Joachim Friske (Contributor), Michaela Hejl (Contributor), Anton Legin (Contributor), Michael Jakupec (Contributor), Bernhard Keppler (Contributor), Werner Lubitz (Contributor), Thomas H Helbich (Contributor) & Juliana IVANOVA-TOUMBEVA (Contributor)

  1 Mar 2023

  Activity: Talks and presentations › Poster presentation › Science to Science

• Accumulation and effects of micro- and nanoplastics in colon carcinoma cells

  Ekaterina Schreiber-Brynzak (Contributor), Elisabeth Schögl (Contributor), Klaudia Cseh (Contributor), Verena Kopatz (Contributor), Andreas Weber (Contributor), Jose Luis Toca-Herrera (Contributor), Michael Jakupec (Contributor), Lukas Kenner (Contributor) & Verena Pichler (Contributor)

  28 Sept 2022

  Activity: Talks and presentations › Poster presentation › Science to Science

• Mn(II) complex of salinomycin – new potential theranostic agent

  Juliana Ivanova (Contributor), Irena Pashkunova-Martic (Contributor), Rositsa Kukeva (Contributor), Radostina Stoyanova (Contributor), Petar Dorkov (Contributor), Joachim Friske (Contributor), Michaela Hejl (Contributor), Michael Jakupec (Contributor), Thomas H Helbich (Contributor) & Bernhard Keppler (Contributor)

  17 Jul 2022

  Activity: Talks and presentations › Poster presentation › Science to Science

• Bioactive ligands as basis for novel tridentate organoruthenium complexes.

  Alexander Rosner (Contributor), Heiko Geisler (Contributor), Julia Westermayr (Contributor), Klaudia Cseh (Contributor), Dominik Wenisch (Contributor), Valentin Fuchs (Contributor), Sophia Harringer (Contributor), Sarah Plutzar (Contributor), Natalie Gajic (Contributor), Michaela Hejl (Contributor), Michael Jakupec (Contributor), Philipp Marquetand (Contributor), Wolfgang Kandioller (Contributor) & Bernhard Keppler (Contributor)

  12 May 2022

  Activity: Talks and presentations › Poster presentation › Science to Science

• Synthesis and initial characterization of Gd(III) complex of salinomycin as a novel theranostic probe for magnetic resonance imaging (MRI)

  Irena Pashkunova-Martic (Contributor), Juliana Ivanova (Contributor), Rositsa Kukeva (Contributor), Radostina Stoyanova (Contributor), Petar Dorkov (Contributor), Joachim Friske (Contributor), Michaela Hejl (Contributor), Michael Jakupec (Contributor), Norbert Kandler (Contributor), Thomas H Helbich (Contributor) & Bernhard Keppler (Contributor)

  7 Oct 2020

  Activity: Talks and presentations › Poster presentation › Science to Science

• Metabolomics in preclinical studies on metal based anticancer drugs

  Mate Rusz (Contributor), Michael Jakupec (Contributor), Bernhard Keppler (Contributor) & Gunda Köllensperger (Contributor)

  16 Sept 2019

  Activity: Talks and presentations › Poster presentation › Science to Science

• High throughput aids quantification in laser ablation

  Andreas Schweikert (Contributor), Sarah Theiner (Contributor), Anna Schöberl (Contributor), Sophie Neumayer (Contributor), Mate Rusz (Contributor), Debora Wernitznig (Contributor), Michael Jakupec (Contributor), Bernhard Keppler (Contributor) & Gunda Köllensperger (Contributor)

  30 Jun 2019

  Activity: Talks and presentations › Poster presentation › Science to Science

• Investigating the quantitative distribution of metal-based anti-cancer drugs in tumour spheroids by LA-ICP-TOF-MS

  Andreas Schweikert (Contributor), Sarah Theiner (Contributor), Debora Wernitznig (Contributor), Michael Jakupec (Contributor), Bernhard Keppler (Contributor) & Gunda Köllensperger (Contributor)

  26 Jun 2018

  Activity: Talks and presentations › Poster presentation › Science to Science

• 4395 / 21 - KP-1339 (IT-139) induces the hallmarks of immunogenic cell death in a colon cancer 3D model in vitro

  Debora Wernitznig (Contributor), Giorgia Del Favero (Contributor), Konstantinos Kiakos (Contributor), Nathalie Harrer (Contributor), Herwig Machat (Contributor), Doris Marko (Contributor), Michael Jakupec (Contributor), Wolfgang Sommergruber (Contributor) & Bernhard Keppler (Contributor)

  14 Apr 2018

  Activity: Talks and presentations › Poster presentation › Science to Science

• KP-1339 (IT-139) Induces Apoptosis and Autophagy in Colon Cancer Cells in Vitro: A 3-Dimensional Perspective

  Klaudia Cseh (Contributor), Debora Wernitznig (Contributor), Konstantinos Kiakos (Contributor), Michael Jakupec (Contributor), Wolfgang Sommergruber (Contributor) & Bernhard Keppler (Contributor)

  11 Mar 2018

  Activity: Talks and presentations › Poster presentation › Science to Science

• Thiomaltol-based organometallic complexes with 1-methylimidazole as leaving group

  Carmen Hackl (Contributor), Melanie Schmidlehner (Contributor), Verena Pichler (Contributor), Maria Novak (Contributor), Alexander Roller (Contributor), Michael Jakupec (Contributor), Wolfgang Kandioller (Contributor) & Bernhard Keppler (Contributor)

  21 Sept 2015

  Activity: Talks and presentations › Poster presentation › Science to Science

• Tetracarboxylatoplatinum(IV) complexes featuring monodentate leaving ligands – a novel class of platinum(IV) prodrugs

  Doris Höfer (Contributor), Hristo Varbanov (Contributor), Anton Legin (Contributor), Michael Jakupec (Contributor), Alexander Roller (Contributor), Galanski, M. S. (Contributor) & Bernhard Keppler (Contributor)

  21 Sept 2015

  Activity: Talks and presentations › Poster presentation › Science to Science

• Low generation PAMAM dendrimers as drug carriers for Pt(IV) complexes

  Nadine Sommerfeld (Contributor), Michaela Hejl (Contributor), Michael Jakupec (Contributor), Galanski, M. S. (Contributor) & Bernhard Keppler (Contributor)

  20 Jul 2015

  Activity: Talks and presentations › Poster presentation › Science to Science

• Thiomaltol-based organometallic complexes with 1-methylimidazole as leaving group: synthesis, stability and biological activity

  Carmen Hackl (Contributor), Melanie Schmidlehner (Contributor), Verena Pichler (Contributor), Maria Novak (Contributor), Alexander Roller (Contributor), Michael Jakupec (Contributor), Wolfgang Kandioller (Contributor) & Bernhard Keppler (Contributor)

  12 Jun 2015

  Activity: Talks and presentations › Poster presentation › Science to Science

• Platinum(IV) derivatives of oxaliplatin: cellular effects and in vivo potency

  Simone Göschl (Contributor), Verena Pichler (Contributor), Ekaterina Schreiber-Brynzak (Contributor), Petra Heffeter (Contributor), Ute Jungwirth (Contributor), Michael Jakupec (Contributor), Walter Berger (Contributor), Mathea Sophia Galanski (Contributor) & Bernhard Keppler (Contributor)

  18 Nov 2014

  Activity: Talks and presentations › Poster presentation › Science to Science

• Behaviour of Platinum(IV) Complexes with Prodrug Function in Different Models of Hypoxia

  Ekaterina Schreiber-Brynzak (Contributor), Verena Pichler (Contributor), Sarah Theiner (Contributor), Petra Heffeter (Contributor), Walter Berger (Contributor), Galanski, M. S. (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  18 Nov 2014

  Activity: Talks and presentations › Poster presentation › Science to Science

• Mixed monodentate tetracarboxylato platinum(IV) complexes featuring a symmetric or unsymmetric coordination sphere

  Doris Höfer (Contributor), Hristo Varbanov (Contributor), Galanski, M. S. (Contributor), Alexander Roller (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  24 Aug 2014

  Activity: Talks and presentations › Poster presentation › Science to Science

• Improved reaction conditions for the synthesis of new NKP–1339 derivatives and preliminary investigations on their anticancer potential

  Paul-Steffen Kuhn (Contributor), Verena Pichler (Contributor), Alexander Roller (Contributor), Michael Jakupec (Contributor), Wolfgang Kandioller (Contributor) & Bernhard Keppler (Contributor)

  Aug 2014

  Activity: Talks and presentations › Poster presentation › Science to Science

• Naphthoquinone derivatives as a bioactive ligand scaffold for the development of organometallic metallodrugs

  Carmen Hackl (Contributor), Michael Jakupec (Contributor), Wolfgang Kandioller (Contributor), Christian G. Hartinger (Contributor) & Bernhard Keppler (Contributor)

  Aug 2014

  Activity: Talks and presentations › Poster presentation › Science to Science

• Synthesis, characterization and anticancer activity of (thio)pyrone-derived organometallic complexes

  Melanie Schmidlehner (Contributor), Verena Pichler (Contributor), Alexander Roller (Contributor), Michael Jakupec (Contributor), Wolfgang Kandioller (Contributor) & Bernhard Keppler (Contributor)

  Aug 2014

  Activity: Talks and presentations › Poster presentation › Science to Science

• A novel class of bis- and tris-chelate diam(m)inebis(dicarboxylato)platinum(IV) complexes as potential anticancer prodrugs.

  Hristo Varbanov (Contributor), Simone Göschl (Contributor), Petra Heffeter (Contributor), Sarah Theiner (Contributor), Alexander Roller (Contributor), Frank Jensen (Contributor), Michael Jakupec (Contributor), Walter Berger (Contributor), Mathea Sophia Galanski (Contributor) & Bernhard Keppler (Contributor)

  22 Jul 2014

  Activity: Talks and presentations › Poster presentation › Science to Science

• Platinum(IV) compounds featuring one or two axial ferrocene bearing ligands: Synthesis, characterization, and cytotoxicity

  Jelena Banfic (Contributor), Anton Legin (Contributor), Michael Jakupec (Contributor), Galanski, M. S. (Contributor) & Bernhard Keppler (Contributor)

  22 Jul 2014

  Activity: Talks and presentations › Poster presentation › Science to Science

• Influence of N-heterocycles on stability and solubility of novel (thio)maltol-derived metal arene complexes: Synthesis, characterization and cytotoxicity

  Melanie Schmidlehner (Contributor), Verena Pichler (Contributor), Alexander Roller (Contributor), Michael Jakupec (Contributor), Wolfgang Kandioller (Contributor) & Bernhard Keppler (Contributor)

  Jul 2014

  Activity: Talks and presentations › Poster presentation › Science to Science

• Synthesis, characterization and preliminary in vitro studies of platinum(IV) compounds featuring one or two axial ferrocene bearing ligands

  Jelena Banfic (Contributor), Anton Legin (Contributor), Michael Jakupec (Contributor), Galanski, M. S. (Contributor) & Bernhard Keppler (Contributor)

  29 May 2014

  Activity: Talks and presentations › Poster presentation › Science to Science

• Influence of reducing agents on the activity of PtIV complexes

  Verena Pichler (Contributor), Simone Göschl (Contributor), Ekaterina Schreiber-Brynzak (Contributor), Michael Jakupec (Contributor), Galanski, M. S. (Contributor) & Bernhard Keppler (Contributor)

  28 Apr 2014

  Activity: Talks and presentations › Poster presentation › Science to Science

• Novel Metal(II) Arene 2-Pyridinecarbothioamides (PCAs): A Rationale to Orally Active Organometallic Anticancer Agents

  Samuel Matthias Meier (Contributor), Muhammad Hanif (Contributor), Zhenita Adhireksan (Contributor), Verena Pichler (Contributor), Maria Novak (Contributor), Elisabeth Jirkovsky (Contributor), Michael Jakupec (Contributor), Vladimir Arion (Contributor), Curt A. Davey (Contributor), Bernhard Keppler (Contributor) & Christian G. Hartinger (Contributor)

  22 Jul 2013

  Activity: Talks and presentations › Poster presentation › Science to Science

• X-ray absorption study on an investigational redox-active Ruthenium anticancer drug

  Alfred Hummer (Contributor), Caroline Bartel (Contributor), Paul-Steffen Kuhn (Contributor), Michael Jakupec (Contributor), Bernhard Keppler (Contributor) & Annette Rompel (Contributor)

  2012

  Activity: Talks and presentations › Poster presentation › Other

• Terminal dimethyl substitution of Triapine leads to activation of CHOP and induction of apoptosis via ER stress in human colon cancer cells

  Robert Trondl (Contributor), Christian Kowol (Contributor), Vladimir Arion (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2011

  Activity: Talks and presentations › Poster presentation › Other

• Synthesis and investigation of substituted RAPTA compounds new potential anticancer drugs

  Maria Babak (Contributor), Samuel Matthias Meier (Contributor), Anton Legin (Contributor), Michael Jakupec (Contributor), Paul J. Dyson (Contributor), Bernhard Keppler (Contributor) & Christian Hartinger (Contributor)

  2011

  Activity: Talks and presentations › Poster presentation › Other

• X-RaY ABSORPTION SPECTROSCOPY ON TUMOR INHIBITING METAL COMPLEXES

  Alfred Hummer (Contributor), Caroline Bartel (Contributor), Vladimir Arion (Contributor), Michael Jakupec (Contributor), Bernhard Keppler (Contributor) & Annette Rompel (Contributor)

  2011

  Activity: Talks and presentations › Poster presentation › Other

• Pyrone vs. pyridinone as ligands for Ru-arene anticancer agents

  Wolfgang Kandioller (Contributor), Caroline Bartel (Contributor), Michael Jakupec (Contributor), Alexey Nazarov (Contributor), Christian Hartinger (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• alpha-N-Heterocyclic thiosemicarbazones induce ER stress-mediated CHOP activation

  Robert Trondl (Contributor), Christian Kowol (Contributor), Vladimir Arion (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Influence of arene ligand, metal center and the leaving group on the in vitro anticancer activity of organometallic compounds linked with carbohydrate based ligands

  Alexey Nazarov (Contributor), Christian Hartinger (Contributor), Isabella Berger (Contributor), Michael Jakupec (Contributor), Paul J. Dyson (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Novel platinum(IV) complexes with high cytotoxicity

  Hristo Varbanov (Contributor), Seied Mojtaba Valiahdi (Contributor), Galanski, M. S. (Contributor), Michael Jakupec (Contributor), Vladimir Arion (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Organometallic 3-(1H-benzimidazol-2-yl)-pyrazolo[3,4-b]pyridines: synthesis, structure, spectroscopic characterization, and antiproliferative activity

  Iryna Stepanenko (Contributor), Vladimir Arion (Contributor), Michaela Hejl (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• The influence of electroporation on cytotoxicity of anticancer ruthenium(III) compounds in vitro and in vivo

  Rosana Hudej (Contributor), Maja Cemazar (Contributor), Masa Kanduser (Contributor), Janez Scancar (Contributor), Simona Kranjc (Contributor), Gregor Sersa (Contributor), Damijan Miklavcic (Contributor), Michael Jakupec (Contributor), Bernhard Keppler (Contributor) & Iztok Turel (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Controlling the reactivity of anticancer active organometallic compounds

  Christian Hartinger (Contributor), Alexey Nazarov (Contributor), Isabella Berger (Contributor), Michael Jakupec (Contributor), Paul J. Dyson (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Organometallic ruthenium and osmium complexes with carbohydrate-based ligands as anticancer agents

  Alexey Nazarov (Contributor), Lucienne Juillerat-Jeanneret (Contributor), Christian Hartinger (Contributor), Olivier Zava (Contributor), Michael Jakupec (Contributor), Bernhard Keppler (Contributor) & Paul J. Dyson (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Synthesis, characterization and antiproliferative activity of [OsCl5(Hazole)]- complexes

  Gabriel Büchel (Contributor), Iryna Stepanenko (Contributor), Michaela Hejl (Contributor), Michael Jakupec (Contributor), Vladimir Arion (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Cellular uptake and DNA interaction studies of active trans-platinum anticancer compounds

  Caroline Bartel (Contributor), Yulia Scaffidi-Domianello (Contributor), Kristof Meelich (Contributor), Nikolay Kukushkin (Contributor), Michael Jakupec (Contributor), Vadim Yu Kukushkin (Contributor), Galanski, M. S. (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Metallorganic indolobenzazepines versus indoloquinolines: the impact of ligand planarity on physico-chemical and biological properties

  Lukas Filak (Contributor), Gerhard Mühlgassner (Contributor), Michael Jakupec (Contributor), Vladimir Arion (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Organoruthenium Cdk inhibitors with a chance to be delivered by a carrier protein molecule (rHSA) to cancer cells

  Iryna Stepanenko (Contributor), Vladimir Arion (Contributor), Maria Novak (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2010

  Activity: Talks and presentations › Poster presentation › Science to Science

• Subcellular distribution study by means of the inherent fluorescence of the investigational drug Triapine and its zinc(II) complex

  Robert Trondl (Contributor), Christian Kowol (Contributor), Vladimir Arion (Contributor), Michael Jakupec (Contributor), Irene Lichtscheidl-Schultz (Contributor) & Bernhard Keppler (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Other

• Cytotoxic effect of the ruthenium compound KP1339 potentiated by electroporation

  Rosana Hudej (Contributor), Iztok Turel (Contributor), Maja Cemazar (Contributor), Masa Kanduser (Contributor), Simona Kranjc (Contributor), Damijan Miklavcic (Contributor), Gregor Sersa (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Science to Science

• The cytotoxic potential of 4-pyrone and 4-thiopyrone derived Ru(II)-cymene complexes and their behaviour in aqueous solution

  Wolfgang Kandioller (Contributor), Christian Hartinger (Contributor), Alexey Nazarov (Contributor), Roland John (Contributor), Caroline Bartel (Contributor), Matthias Skocic (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Science to Science

• The gallium complex KP46 exerts strong activity against primary explanted melanoma cells and induces apoptosis in melanoma cell lines

  Seied Mojtaba Valiahdi (Contributor), Petra Heffeter (Contributor), Michael Jakupec (Contributor), Rodrig Marculescu (Contributor), Walter Berger (Contributor), Klemens Rappersberger (Contributor) & Bernhard Keppler (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Science to Science

• New insights into the mechanisms underlying the anticancer activity of the gallium compound NKP46: impact of DNA damage

  Ute Jungwirth (Contributor), Petra Heffeter (Contributor), Rita Dornetshuber (Contributor), Seied Mojtaba Valiahdi (Contributor), Michael Jakupec (Contributor), Leonilla Elbling (Contributor), Michael Micksche (Contributor), Bernhard Keppler (Contributor) & Walter Berger (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Science to Science

• The Ga coordination sphere of KP46 in solution and in cancer cells - a XAS investigation

  Annette Rompel (Contributor), Ana Mijovilovich (Contributor), Wolfram Meyer-Klaucke (Contributor), Ladislav Novotny (Contributor), Michael Jakupec (Contributor) & Bernhard Keppler (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Science to Science

• Novel mono-substituted oxaliplatin analogs with improved Characteristics

  Ute Jungwirth (Contributor), Petra Heffeter (Contributor), Michael Jakupec (Contributor), Galanski, M. S. (Contributor), Wilfried Körner (Contributor), Michael Micksche (Contributor), Bernhard Keppler (Contributor) & Walter Berger (Contributor)

  2009

  Activity: Talks and presentations › Poster presentation › Science to Science