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Dive into the research topics where Palle Steen Helmke is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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A broad kinase inhibitor library live cell imaging screen using liver, kidney and cardiac hiPSC-ICAM1-eGFP reporter lineages identifies liabilities for TNFα pathway modulation
Vlasveld, M., van den Berk, L., Piñero, J., Helmke, P. S., Ecker, G. F., van Rossom, R., Schmidt, B. Z., Verfaillie, C., Tassis, K., Callegaro, G., Bouwman, P. & van de Water, B., 5 Nov 2025, (E-pub ahead of print) In: Archives of Toxicology. 100, 2, p. 585-601 17 p.Publications: Contribution to journal › Article › Peer Reviewed
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Data-driven assessment of bioisosteric replacements and their influence on off-target activity profiles
Helmke, P. S., Kandler, J., Ilie, S., Gaskin, L. & Ecker, G. F. (Corresponding author), 10 Dec 2025, In: RSC Medicinal Chemistry. 16, 12, p. 6048-6058 11 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Moving towards making (quantitative) structure-activity relationships ((Q)SARs) for toxicity-related endpoints findable, accessible, interoperable and reusable (FAIR)
Belfield, S. J., Basiri, H., Swapnil, C., Chrysochoou, G., Enoch, S. J., Firman, J. W., Gomatam, A., Hardy, B., Helmke, P. S., Madden, J. C., Maran, U., March-Vila, E., Nikolov, N. G., Pastor, M., Piir, G., Sild, S., Smajić, A., Spînu, N., Wedebye, E. B. & Cronin, M. T. D. (Corresponding author), 2025, In: Altex. 42, 4, p. 657-666 10 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access