Publications per year
Publications per year
- 33 results
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2024
A Targeted, Bioinert LC-MS/MS Method for Sensitive, Comprehensive Analysis of Signaling Lipids
Rubenzucker, S., Manke, M. C., Lehmann, R., Assinger, A., Borst, O. & Ahrends, R., 11 Jun 2024, In: Analytical Chemistry. 96, 23, p. 9643-9652 10 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards
National Institute of Standards and Technology, Torta, F., Hoffmann, N., Burla, B., Alecu, I., Arita, M., Bamba, T., Bennett, S. A. L., Bertrand-Michel, J., Brügger, B., Cala, M. P., Camacho-Muñoz, D., Checa, A., Chen, M., Chocholoušková, M., Cinel, M., Chu-Van, E., Colsch, B., Coman, C., Connell, L., & 32 others, Dec 2024, In: Nature Communications. 15, 1, 8562.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Eye proteome of Drosophila melanogaster
Kumar, M., Has, C., Lam-Kamath, K., Ayciriex, S., Dewett, D., Bashir, M., Poupault, C., Schuhmann, K., Thomas, H., Knittelfelder, O., Raghuraman, B. K., Ahrends, R., Rister, J. & Shevchenko, A., May 2024, In: Proteomics. 24, 10, 2300330.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Lipidome Unsaturation Affects the Morphology and Proteome of the Drosophila Eye
Kumar, M., Has, C., Lam-Kamath, K., Ayciriex, S., Dewett, D., Bashir, M., Poupault, C., Schuhmann, K., Thomas, H., Knittelfelder, O., Raghuraman, B. K., Ahrends, R., Rister, J. & Shevchenko, A., 5 Apr 2024, In: Journal of Proteome Research. 23, 4, p. 1188-1199 12 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Targeting Sphingosine-1-Phosphate Signaling to Prevent the Progression of Aortic Valve Disease
Benkhoff, M., Barcik, M., Mourikis, P., Dahlmanns, J., Kahmann, P., Wollnitzke, P., Hering, M., Huckenbeck, T., Hoppe, J., Semleit, N., Deister-Jonas, J., Zako, S., Seel, J., Coman, C., Barth, M., Cramer, M., Helten, C., Wildeis, L., Hu, H., Al-Kassis, G., & 15 others, 2024, (E-pub ahead of print) In: Circulation.Publications: Contribution to journal › Article › Peer Reviewed
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The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data
Kopczynski, D., Ejsing, C. S., McDonald, J. G., Bamba, T., Baker, E. S., Bertrand-Michel, J., Brügger, B., Coman, C., Ellis, S. R., Garrett, T. J., Griffiths, W. J., Guan, X. L., Han, X., Höring, M., Holčapek, M., Hoffmann, N., Huynh, K., Lehmann, R., Jones, J. W., Kaddurah-Daouk, R., & 16 others, Sept 2024, In: Journal of Lipid Research. 65, 9, 100621.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
2023
Accurate Sphingolipid Quantification Reducing Fragmentation Bias by Nonlinear Models
Troppmair, N., Kopczynski, D., Assinger, A., Lehmann, R., Coman, C. & Ahrends, R., Oct 2023, In: Analytical Chemistry. 95, 41, p. 15227-15235 9 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Critical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation
de Jonckheere, B., Kollotzek, F., Münzer, P., Göb, V., Fischer, M., Mott, K., Coman, C., Troppmair, N. N., Manke, M. C., Zdanyte, M., Harm, T., Sigle, M., Kopczynski, D., Bileck, A., Gerner, C., Hoffmann, N., Heinzmann, D., Assinger, A., Gawaz, M., Stegner, D., & 3 others, Sept 2023, In: Nature Cardiovascular Research. 2, 9, p. 835-852 18 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Ex vivo instability of lipids in whole blood: preanalytical recommendations for clinical lipidomics studies
Wang, Q., Hoene, M., Hu, C., Fritsche, L., Ahrends, R., Liebisch, G., Ekroos, K., Fritsche, A., Birkenfeld, A. L., Liu, X., Zhao, X., Li, Q., Su, B., Peter, A., Xu, G. & Lehmann, R., Jun 2023, In: Journal of Lipid Research. 64, 6, 100378.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Flexible Microtube Plasma for the Consecutive-Ionization of Cholesterol in Nano-Electrospray Mass Spectrometry
Foest, D., Knodel, A., Ahrends, R., Coman, C., Franzke, J. & Brandt, S., 6 Jun 2023, In: Analytical Chemistry. 95, 22, p. 8423-8432 10 p.Publications: Contribution to journal › Article › Peer Reviewed
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Guiding the choice of informatics software and tools for lipidomics research applications
Ni, Z., Wolk, M., Jukes, G., Espinosa, K. M., Ahrends, R., Aimo, L., Alvarez-Jarreta, J., Andrews, S., Andrews, R., Bridge, A., Clair, G. C., Conroy, M. J., Fahy, E., Gaud, C., Goracci, L., Hartler, J., Hoffmann, N., Kopczynski, D., Korf, A., Lopez-Clavijo, A. F., & 14 others, Feb 2023, In: Nature Methods. 20, 2, p. 193-204 12 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
High-throughput assessment identifying major platelet Ca2+ entry pathways via tyrosine kinase-linked and G protein-coupled receptors
Cheung, H. Y. F., Zou, J., Tantiwong, C., Fernandez, D. I., Huang, J., Ahrends, R., Roest, M., Cavill, R., Gibbins, J. & Heemskerk, J. W. M., Jun 2023, In: Cell Calcium. 112, 102738.Publications: Contribution to journal › Article › Peer Reviewed
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LipidSpace: Simple Exploration, Reanalysis, and Quality Control of Large-Scale Lipidomics Studies
Kopczynski, D., Hoffmann, N., Troppmair, N., Coman, C., Ekroos, K., Kreutz, M. R., Liebisch, G., Schwudke, D. & Ahrends, R., 4 Oct 2023, In: Analytical Chemistry. 95, 41, p. 15236-15244 9 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Quantification of bulk lipid species in human platelets and their thrombin-induced release
Heimerl, S., Höring, M., Kopczynski, D., Sigruener, A., Hart, C., Burkhardt, R., Black, A., Ahrends, R. & Liebisch, G., Dec 2023, In: Scientific Reports. 13, 1, 6154.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
2022
Analytical comparison of absolute quantification strategies to investigate the Insulin signaling pathway in fat cells
Li, T., Hentschel, A. & Ahrends, R., Apr 2022, In: Proteomics. 22, 7, 11 p., e2100136.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Goslin 2.0 Implements the Recent Lipid Shorthand Nomenclature for MS-Derived Lipid Structures
Kopczynski, D., Hoffmann, N., Peng, B., Liebisch, G., Spener, F. & Ahrends, R., 26 Apr 2022, In: Analytical Chemistry. 94, 16, p. 6097-6101 5 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Introducing the Lipidomics Minimal Reporting Checklist
McDonald, J. G., Ejsing, C. S., Kopczynski, D., Holcapek, M., Aoki, J., Arita, M., Arita, M., Baker, E. S., Bertrand-Michel, J., Bowden, J. A., Brugger, B., Ellis, S. R., Fedorova, M., Griffiths, W. J., Han, X., Hartler, J., Hoffmann, N., Koelmel, J. P., Kofeler, H. C., Mitchell, T. W., & 12 others, Aug 2022, In: Nature Metabolism. 4, 9, p. 1086-1088 3 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Lipidomic profiling of human serum enables detection of pancreatic cancer
Wolrab, D., Jirasko, R., Cifkova, E., Horing, M., Mei, D., Chocholouskova, M., Peterka, O., Idkowiak, J., Hrnciarova, T., Kuchar, L., Ahrends, R., Brumarova, R., Friedecky, D., Vivo-Truyols, G., Skrha, P., Skrha, J., Kucera, R., Melichar, B., Liebisch, G., Burkhardt, R., & 7 others, 10 Jan 2022, In: Nature Communications. 13, 1, 16 p., 124.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer's disease
Confettura, A. D., Cuboni, E., Ammar, M. R., Jia, S., Gomes, G. M., Yuanxiang, P., Raman, R., Li, T., Grochowska, K. M., Ahrends, R., Karpova, A., Dityatev, A. & Kreutz, M. R., 6 Jan 2022, In: Translational neurodegeneration. 11, 1, 18 p., 2.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Targeting early stages of cardiotoxicity from anti-PD1 immune checkpoint inhibitor therapy
Michel, L., Helfrich, I., Hendgen-Cotta, U. B., Mincu, R-I., Korste, S., Mrotzek, S. M., Spomer, A., Odersky, A., Rischpler, C., Herrmann, K., Umutlu, L., Coman, C., Ahrends, R., Sickmann, A., Löffek, S., Livingstone, E., Ugurel, S., Zimmer, L., Gunzer, M., Schadendorf, D., & 2 others, 21 Jan 2022, In: European Heart Journal. 43, 4, p. 316-329 15 p.Publications: Contribution to journal › Article › Peer Reviewed
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Vitamin A Deficiency Alters the Phototransduction Machinery and Distinct Non-Vision-Specific Pathways in the Drosophila Eye Proteome
Kumar, M., Has, C., Lam-Kamath, K., Ayciriex, S., Dewett, D., Bashir, M., Poupault, C., Schuhmann, K., Knittelfelder, O., Raghuraman, B. K., Ahrends, R., Rister, J. & Shevchenko, A., Aug 2022, In: Biomolecules. 12, 8, 18 p., 1083.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
2021
ANXA7 Regulates Platelet Lipid Metabolism and Ca2+ Release in Arterial Thrombosis
Manke, M-C., Geue, S., Coman, C., Peng, B., Kollotzek, F., Muenzer, P., Walker, B., Huber, S. M., Rath, D., Sickmann, A., Stegner, D., Duerschmied, D., Lang, F., Nieswandt, B., Gawaz, M., Ahrends, R. & Borst, O., 6 Aug 2021, In: Circulation Research. 129, 4, p. 494-507 14 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment
Borgmeyer, M., Coman, C., Has, C., Schoett, H-F., Li, T., Westhoff, P., Cheung, Y. F. H., Hoffmann, N., Yuanxiang, P., Behnisch, T., Gomes, G. M., Dumenieu, M., Schweizer, M., Chocholouskova, M., Holcapek, M., Mikhaylova, M., Kreutz, M. R. & Ahrends, R., 5 Oct 2021, In: Cell Reports. 37, 1, 28 p., 109797.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Targeted Phosphoinositides Analysis Using High-Performance Ion Chromatography-Coupled Selected Reaction Monitoring Mass Spectrometry
Cheung, H. Y. F., Coman, C., Westhoff, P., Manke, M., Sickmann, A., Borst, O., Gawaz, M., Watson, S. P., Heemskerk, J. W. M. & Ahrends, R., 4 Jun 2021, In: Journal of Proteome Research. 20, 6, p. 3114-3123 10 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
2020
A multi-omics analysis reveals the unfolded protein response regulon and stress-induced resistance to folate-based antimetabolites
Reich, S., Nguyen, C. D. L., Has, C., Steltgens, S., Soni, H., Coman, C., Freyberg, M., Bichler, A., Seifert, N., Conrad, D., Knobbe-Thomsen, C. B., Tews, B., Toedt, G., Ahrends, R. & Medenbach, J., 10 Jun 2020, In: Nature Communications. 11, 1, 15 p., 2936.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Developing a Robust Assay to Monitor and Quantify Key Players of Metabolic Pathways during Adipogenesis by Targeted Proteomics
Hentschel, A. & Ahrends, R., Jun 2020, In: Proteomics. 20, 11, 10 p., 1900141.Publications: Contribution to journal › Article › Peer Reviewed
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Goslin: A Grammar of Succinct Lipid Nomenclature
Kopczynski, D., Hoffmann, N., Peng, B. & Ahrends, R., 18 Aug 2020, In: Analytical Chemistry. 92, 16, p. 10957-10960 4 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
LipidCreator workbench to probe the lipidomic landscape
Peng, B., Kopczynski, D., Pratt, B. S., Ejsing, C. S., Burla, B., Hermansson, M., Benke, P. I., Tan, S. H., Chan, M. Y., Torta, F., Schwudke, D., Meckelmann, S. W., Coman, C., Schmitz, O. J., MacLean, B., Manke, M-C., Borst, O., Wenk, M. R., Hoffmann, N. & Ahrends, R., 28 Apr 2020, In: Nature Communications. 11, 1, 14 p., 2057.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome
van Geffen, J. P., Swieringa, F., van Kuijk, K., Tullemans, B. M. E., Solari, F. A., Peng, B., Clemetson, K. J., Farndale, R. W., Dubois, L. J., Sickmann, A., Zahedi, R. P., Ahrends, R., Biessen, E. A. L., Sluimer, J. C., Heemskerk, J. W. M. & Kuijpers, M. J. E., 8 Dec 2020, In: Scientific Reports. 10, 1, 17 p., 21407.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
PERK-mediated expression of peptidylglycine α-amidating monooxygenase supports angiogenesis in glioblastoma
Soni, H., Bode, J., Nguyen, C. D. L., Puccio, L., Nessling, M., Piro, R. M., Bub, J., Phillips, E., Ahrends, R., Eipper, B. A., Tews, B. & Goidts, V., 13 Feb 2020, In: Oncogenesis. 9, 2, 16 p., 18.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Simple Targeted Assays for Metabolic Pathways and Signaling: A Powerful Tool for Targeted Proteomics
Kopczynski, D., Hentschel, A., Coman, C., Schebb, N. H., Hornemann, T., Mashek, D. G., Hartung, N. M., Shevchuk, O., Schott, H-F., Lorenz, K., Torta, F., Burla, B., Zahedi, R. P., Sickmann, A., Kreutz, M. R., Ejsing, C. S., Medenbach, J. & Ahrends, R., 20 Oct 2020, In: Analytical Chemistry. 92, 20, p. 13672-13676 5 p.Publications: Contribution to journal › Article › Peer Reviewed
Open Access -
Uncovering the complexity of the yeast lipidome by means of nLC/NSI-MS/MS
Danne-Rasche, N., Rubenzucker, S. & Ahrends, R., 15 Dec 2020, In: Analytica Chimica Acta. 1140, p. 199-209 11 p.Publications: Contribution to journal › Article › Peer Reviewed
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2019
jmzTab-M: A Reference Parser, Writer, and Validator for the Proteomics Standards Initiative mzTab 2.0 Metabolomics Standard
Hoffmann, N., Hartler, J. & Ahrends, R., 15 Oct 2019, In: Analytical Chemistry. 91, 20, p. 12615-12618 4 p.Publications: Contribution to journal › Article › Peer Reviewed