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β subunits of GABAA receptors form proton-gated chloride channels: Insights into the molecular basis

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Article number784
Number of pages10
JournalCommunications Biology
Volume5
Issue number1
DOIs
Publication statusPublished - 3 Aug 2022

Funding

We thank Eugen Timin for comments on the manuscript. Dinah Weissmann and Christopher Cayzac from ALCEDIAG kindly supplied SH-SY5Y cells. This study was supported by the doctoral programme “Molecular drug targets” W1232 (A.G., T.F., M.S., M.E., A.S.-W., S.H.), the Post-Doc programme “Zukunftskolleg” ZK-81B of the Austrian Science Fund (FWF) (T.F. and E.-M.Z.-P.) and the DOC fellowship 26156 of the Austrian Academy of Sciences (ÖAW) (T.F.). We thank Morten Jensen and Vishwanath Jogini from D. E. Shaw Research for valuable suggestions. We thank Eugen Timin for comments on the manuscript. Dinah Weissmann and Christopher Cayzac from ALCEDIAG kindly supplied SH-SY5Y cells. This study was supported by the doctoral programme “Molecular drug targets” W1232 (A.G., T.F., M.S., M.E., A.S.-W., S.H.), the Post-Doc programme “Zukunftskolleg” ZK-81B of the Austrian Science Fund (FWF) (T.F. and E.-M.Z.-P.) and the DOC fellowship 26156 of the Austrian Academy of Sciences (ÖAW) (T.F.). We thank Morten Jensen and Vishwanath Jogini from D. E. Shaw Research for valuable suggestions.

Austrian Fields of Science 2012

  • 301206 Pharmacology

Keywords

  • GAMMA-AMINOBUTYRIC-ACID
  • ION CHANNELS
  • BINDING-SITE
  • TM2 RESIDUE
  • MODULATION
  • SIMULATIONS
  • BETA-1-SUBUNIT
  • PHARMACOLOGY
  • SUBTYPES
  • PH

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