A robust and miniaturized screening platform to study natural products affecting metabolism and survival in Caenorhabditis elegans

Julia Zwirchmayr; Benjamin Kirchweger; Theresa Lehner; Ammar Tahir; Dagmar Pretsch; Judith M. Rollinger

doi:10.1038/s41598-020-69186-6

A robust and miniaturized screening platform to study natural products affecting metabolism and survival in Caenorhabditis elegans

Julia Zwirchmayr
, Benjamin Kirchweger
, Theresa Lehner
, Ammar Tahir
, Dagmar Pretsch
, Judith M. Rollinger

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Article number	12323
Journal	Scientific Reports
Volume	10
Issue number	1
DOIs	https://doi.org/10.1038/s41598-020-69186-6
Publication status	Published - 23 Jul 2020

Funding

DP is funded by a DOC-scholarship provided from the Austrian Academy of Science, Dr. Ignaz Seipel-Platz 2, 1010 Vienna. TL is partly supported by a project of the Austrian Drug Screening Institute. The authors thank Dietmar Pum from the University of Natural Ressources and Life Sciences for providing expertise in the field of image processing; and diploma students Agnes Wieser, Kevin Meszaros and Martina Redl for their technical support.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Austrian Fields of Science 2012

301204 Pharmacognosy

Keywords

HIGH-FAT DIET
LIFE-SPAN EXTENSION
C. ELEGANS
DRUG DISCOVERY
DIMETHYL-SULFOXIDE
INONOTUS-OBLIQUUS
MODEL
CHEMISTRY
INCREASE
STRESS

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10.1038/s41598-020-69186-6Licence: CC BY 4.0

https://phaidra.univie.ac.at/o:1212800Licence: CC BY 4.0

Cite this

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title = "A robust and miniaturized screening platform to study natural products affecting metabolism and survival in Caenorhabditis elegans",

keywords = "HIGH-FAT DIET, LIFE-SPAN EXTENSION, C. ELEGANS, DRUG DISCOVERY, DIMETHYL-SULFOXIDE, INONOTUS-OBLIQUUS, MODEL, CHEMISTRY, INCREASE, STRESS",

author = "Julia Zwirchmayr and Benjamin Kirchweger and Theresa Lehner and Ammar Tahir and Dagmar Pretsch and Rollinger, \{Judith M.\}",

note = "Funding Information: DP is funded by a DOC-scholarship provided from the Austrian Academy of Science, Dr. Ignaz Seipel-Platz 2, 1010 Vienna. TL is partly supported by a project of the Austrian Drug Screening Institute. The authors thank Dietmar Pum from the University of Natural Ressources and Life Sciences for providing expertise in the field of image processing; and diploma students Agnes Wieser, Kevin Meszaros and Martina Redl for their technical support. Publisher Copyright: {\textcopyright} 2020, The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",

year = "2020",

month = jul,

day = "23",

doi = "10.1038/s41598-020-69186-6",

language = "English",

volume = "10",

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AU - Zwirchmayr, Julia

AU - Kirchweger, Benjamin

AU - Lehner, Theresa

AU - Tahir, Ammar

AU - Pretsch, Dagmar

AU - Rollinger, Judith M.

N1 - Funding Information: DP is funded by a DOC-scholarship provided from the Austrian Academy of Science, Dr. Ignaz Seipel-Platz 2, 1010 Vienna. TL is partly supported by a project of the Austrian Drug Screening Institute. The authors thank Dietmar Pum from the University of Natural Ressources and Life Sciences for providing expertise in the field of image processing; and diploma students Agnes Wieser, Kevin Meszaros and Martina Redl for their technical support. Publisher Copyright: © 2020, The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

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KW - HIGH-FAT DIET

KW - LIFE-SPAN EXTENSION

KW - C. ELEGANS

KW - DRUG DISCOVERY

KW - DIMETHYL-SULFOXIDE

KW - INONOTUS-OBLIQUUS

KW - MODEL

KW - CHEMISTRY

KW - INCREASE

KW - STRESS

UR - https://www.scopus.com/pages/publications/85088499998

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DO - 10.1038/s41598-020-69186-6

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AN - SCOPUS:85088499998

SN - 2045-2322

VL - 10

JO - Scientific Reports

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M1 - 12323

ER -

A robust and miniaturized screening platform to study natural products affecting metabolism and survival in Caenorhabditis elegans

Funding

UN SDGs

Austrian Fields of Science 2012

Keywords

Access to Document

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