A Robust, Eco-Friendly Access to Secondary Thioamides through the Addition of Organolithium Reagents to Isothiocyanates in Cyclopentyl Methyl Ether (CPME)

Vittorio Pace (Corresponding author), Laura Castoldi, Serena Monticelli, Sandra Safranek, Alexander Roller, Thierry Langer, Wolfgang Holzer

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Pages (from-to)18966-18970
Number of pages5
JournalChemistry: A European Journal
Volume21
Issue number52
DOIs
Publication statusPublished - 20 Nov 2015

Austrian Fields of Science 2012

  • 301207 Pharmaceutical chemistry
  • 104003 Inorganic chemistry
  • 104015 Organic chemistry

Keywords

  • isothiocyanates
  • lithiation
  • nucleophilic addition
  • one-pot synthesis
  • thioamides
  • GRIGNARD-REAGENTS
  • SEQUENTIAL REACTIONS
  • ELEMENTAL SULFUR
  • BORONIC ESTERS
  • ALDOL REACTION
  • AMIDES
  • THIOFORMAMIDES
  • ISOCYANATES
  • AMINES
  • 2-METHYLTETRAHYDROFURAN

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