A Simple Synthesis of 6-Phenylpyrano[2,3-c]pyrazol-4(1H)-ones

Gernot Eller, Wolfgang Holzer (Corresponding author)

    Publications: Contribution to journalArticlePeer Reviewed

    Abstract

    A novel synthesis of substituted 6-phenylpyrano[2,3-c]pyrazol-4(1H)-ones via reaction of various 2-substituted or 2,5-disubstituted 2,4-dihydro-3H-pyrazol-3-ones with phenylpropyn­oyl chloride using calcium hydroxide in refluxing 1,4-dioxane is described. N-Unsubstituted representatives were obtained by treatment of 4-methoxybenzyl-protected congeners with trifluoroacetic acid.
    Original languageEnglish
    Pages (from-to)2583-2589
    Number of pages7
    JournalSynthesis: journal of synthetic organic chemistry
    Issue number15
    Publication statusPublished - 2005

    Austrian Fields of Science 2012

    • 301207 Pharmaceutical chemistry

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