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A structure-kinetic relationship study using matched molecular pair analysis

  • Doris A. Schuetz
  • , Lars Richter
  • , Riccardo Martini
  • , Gerhard F. Ecker (Corresponding author)

    Publications: Contribution to journalArticlePeer Reviewed

    Original languageEnglish
    Pages (from-to)1285-1294
    Number of pages10
    JournalRSC Medicinal Chemistry
    Volume11
    Issue number11
    Early online date21 Sept 2020
    DOIs
    Publication statusPublished - 2020

    Funding

    This work was supported by the EU/EFPIA Innovative Medicines Initiative (IMI) Joint Undertaking, K4DD (grant no. 1115366). This paper reflects only the authors' views and neither the IMI nor the European Commission is liable for any use that may be made of the information contained herein. Furthermore, we want to thank Bernhard Knasmuller for support on the methodologies for the database structure.

    Austrian Fields of Science 2012

    • 301207 Pharmaceutical chemistry

    Keywords

    • TARGET RESIDENCE TIME
    • BINDING-KINETICS
    • IN-VIVO
    • ATYPICAL ANTIPSYCHOTICS
    • DRUG DISCOVERY
    • RECEPTOR
    • INHIBITORS
    • SELECTIVITY
    • KINASE
    • DISSOCIATION

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