Adenoviral Vectors Coated with PAMAM Dendrimer Conjugates Allow CAR Independent Virus Uptake and Targeting to the EGF Receptor

Alexandra Vetter, Kulpreet S. Virdi, Sigrid Espenlaub, Wolfgang Roedl, Ernst Wagner, Per S. Holm, Christina Scheu, Florian Kreppel, Christine Spitzweg, Manfred Ogris

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Pages (from-to)606-618
Number of pages13
JournalMolecular Pharmaceutics
Volume10
Issue number2
DOIs
Publication statusPublished - Feb 2013
Externally publishedYes

Austrian Fields of Science 2012

  • 301207 Pharmaceutical chemistry

Keywords

  • adenovirus
  • PAMAM dendrimer
  • EGFR targeting
  • GE11 peptide
  • CAR
  • GROWTH-FACTOR RECEPTOR
  • GENE-TRANSFER
  • IN-VITRO
  • LINEAR POLYETHYLENIMINE
  • OVARIAN-CANCER
  • DELIVERY
  • CELLS
  • THERAPEUTICS
  • POLYMERS
  • THERAPY

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