Alum triggers infiltration of human neutrophils ex vivo and causes lysosomal destabilization and mitochondrial membrane potential-dependent NET-formation

Manuel Reithofer; Jasmine Karacs; Johanna Strobl; Claudia Kitzmueller; Dominika Polak; Katharina Seif; Meder Kamalov; Christian F. W. Becker; Georg Greiner; Klaus Schmetterer; Georg Stary; Barbara Bohle; Beatrice Jahn-Schmid

doi:10.1096/fj.202001413R

Alum triggers infiltration of human neutrophils ex vivo and causes lysosomal destabilization and mitochondrial membrane potential-dependent NET-formation

Manuel Reithofer, Jasmine Karacs, Johanna Strobl, Claudia Kitzmueller, Dominika Polak, Katharina Seif, Meder Kamalov, Christian F. W. Becker, Georg Greiner, Klaus Schmetterer, Georg Stary, Barbara Bohle, Beatrice Jahn-Schmid (Corresponding author)

Department of Biological Chemistry

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Pages (from-to)	14024-14041
Number of pages	18
Journal	The FASEB Journal
Volume	34
Issue number	10
DOIs	https://doi.org/10.1096/fj.202001413R
Publication status	Published - Oct 2020

Austrian Fields of Science 2012

104004 Chemical biology
301114 Cell biology

Keywords

aluminium hydroxide
vaccine
adjuvant
innate response
neutrophils
NET
EXTRACELLULAR TRAP FORMATION
NLRP3 INFLAMMASOME
NALP3 INFLAMMASOME
DENDRITIC CELLS
RELEASE
ACTIVATION
IMMUNITY
INJECTION
MECHANISM
ADJUVANTS

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1096/fj.202001413R

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Reithofer, M., Karacs, J., Strobl, J., Kitzmueller, C., Polak, D., Seif, K., Kamalov, M., Becker, C. F. W., Greiner, G., Schmetterer, K., Stary, G., Bohle, B., & Jahn-Schmid, B. (2020). Alum triggers infiltration of human neutrophils ex vivo and causes lysosomal destabilization and mitochondrial membrane potential-dependent NET-formation. The FASEB Journal, 34(10), 14024-14041. https://doi.org/10.1096/fj.202001413R

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title = "Alum triggers infiltration of human neutrophils ex vivo and causes lysosomal destabilization and mitochondrial membrane potential-dependent NET-formation",

keywords = "aluminium hydroxide, vaccine, adjuvant, innate response, neutrophils, NET, EXTRACELLULAR TRAP FORMATION, NLRP3 INFLAMMASOME, NALP3 INFLAMMASOME, DENDRITIC CELLS, RELEASE, ACTIVATION, IMMUNITY, INJECTION, MECHANISM, ADJUVANTS",

author = "Manuel Reithofer and Jasmine Karacs and Johanna Strobl and Claudia Kitzmueller and Dominika Polak and Katharina Seif and Meder Kamalov and Becker, {Christian F. W.} and Georg Greiner and Klaus Schmetterer and Georg Stary and Barbara Bohle and Beatrice Jahn-Schmid",

note = "Publisher Copyright: {\textcopyright} 2020 The Authors. The FASEB Journal published by Wiley Periodicals LLC on behalf of Federation of American Societies for Experimental Biology",

year = "2020",

month = oct,

doi = "10.1096/fj.202001413R",

language = "English",

volume = "34",

pages = "14024--14041",

journal = "The FASEB Journal",

issn = "0892-6638",

publisher = "FEDERATION AMER SOC EXP BIOL",

number = "10",

}

Reithofer, M, Karacs, J, Strobl, J, Kitzmueller, C, Polak, D, Seif, K, Kamalov, M, Becker, CFW, Greiner, G, Schmetterer, K, Stary, G, Bohle, B & Jahn-Schmid, B 2020, 'Alum triggers infiltration of human neutrophils ex vivo and causes lysosomal destabilization and mitochondrial membrane potential-dependent NET-formation', The FASEB Journal, vol. 34, no. 10, pp. 14024-14041. https://doi.org/10.1096/fj.202001413R

TY - JOUR

T1 - Alum triggers infiltration of human neutrophils ex vivo and causes lysosomal destabilization and mitochondrial membrane potential-dependent NET-formation

AU - Reithofer, Manuel

AU - Karacs, Jasmine

AU - Strobl, Johanna

AU - Kitzmueller, Claudia

AU - Polak, Dominika

AU - Seif, Katharina

AU - Kamalov, Meder

AU - Becker, Christian F. W.

AU - Greiner, Georg

AU - Schmetterer, Klaus

AU - Stary, Georg

AU - Bohle, Barbara

AU - Jahn-Schmid, Beatrice

PY - 2020/10

Y1 - 2020/10

KW - aluminium hydroxide

KW - vaccine

KW - adjuvant

KW - innate response

KW - neutrophils

KW - NET

KW - EXTRACELLULAR TRAP FORMATION

KW - NLRP3 INFLAMMASOME

KW - NALP3 INFLAMMASOME

KW - DENDRITIC CELLS

KW - RELEASE

KW - ACTIVATION

KW - IMMUNITY

KW - INJECTION

KW - MECHANISM

KW - ADJUVANTS

UR - http://www.scopus.com/inward/record.url?scp=85089970914&partnerID=8YFLogxK

U2 - 10.1096/fj.202001413R

DO - 10.1096/fj.202001413R

M3 - Article

SN - 0892-6638

VL - 34

SP - 14024

EP - 14041

JO - The FASEB Journal

JF - The FASEB Journal

IS - 10

ER -

Alum triggers infiltration of human neutrophils ex vivo and causes lysosomal destabilization and mitochondrial membrane potential-dependent NET-formation

Austrian Fields of Science 2012

Keywords

UN SDGs

Access to Document

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