Amorphous Silica Particles Relevant in Food Industry Influence Cellular Growth and Associated Signaling Pathways in Human Gastric Carcinoma Cells

Anja Wittig; Helge Gehrke; Giorgia Del Favero; Eva-Maria Fritz; Marco Al-Rawi; Silvia Diabate; Carsten Weiss; Haider Sami; Manfred Ogris; Doris Marko

doi:10.3390/nano7010018

Amorphous Silica Particles Relevant in Food Industry Influence Cellular Growth and Associated Signaling Pathways in Human Gastric Carcinoma Cells

Anja Wittig
, Helge Gehrke
, Giorgia Del Favero
, Eva-Maria Fritz
, Marco Al-Rawi
, Silvia Diabate
, Carsten Weiss
, Haider Sami
, Manfred Ogris
, Doris Marko (Corresponding author)

Department of Food Chemistry and Toxicology

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Article number	18
Number of pages	26
Journal	Nanomaterials
Volume	7
Issue number	1
DOIs	https://doi.org/10.3390/nano7010018
Publication status	Published - Jan 2017

Funding

This research received support from the QualityNano Project http://www.qnano-ri.eu which is financed by the European Community Research Infrastructures under the FP7 Capacities Programme (Grant No. INFRA-2010-262163), and its partner Karlsruhe Institute of Technology KIT. This article was supported by the Open Access Publishing Fund of the University of Vienna. Furthermore, we gratefully acknowledge Gergely Solecki and Hermann Bloss for their contribution to experimental measurements.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Austrian Fields of Science 2012

301211 Toxicology
210004 Nanomaterials

Keywords

silica particles
cytotoxicity
proliferation
Ki-67
EGFR and MAPK signaling
gastrointestinal tract
RECEPTOR TYROSINE KINASES
LUNG EPITHELIAL-CELLS
IN-VITRO TOXICITY
OXIDATIVE STRESS
GENE DELIVERY
EGF RECEPTOR
NANOPARTICLES
APOPTOSIS
PROLIFERATION
ACTIVATION
Cytotoxicity
Gastrointestinal tract
Proliferation
Silica particles

Access to Document

10.3390/nano7010018Licence: CC BY 4.0

http://phaidra.univie.ac.at/o:780683Licence: CC BY 4.0

Cite this

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title = "Amorphous Silica Particles Relevant in Food Industry Influence Cellular Growth and Associated Signaling Pathways in Human Gastric Carcinoma Cells",

keywords = "silica particles, cytotoxicity, proliferation, Ki-67, EGFR and MAPK signaling, gastrointestinal tract, RECEPTOR TYROSINE KINASES, LUNG EPITHELIAL-CELLS, IN-VITRO TOXICITY, OXIDATIVE STRESS, GENE DELIVERY, EGF RECEPTOR, NANOPARTICLES, APOPTOSIS, PROLIFERATION, ACTIVATION, Cytotoxicity, Gastrointestinal tract, Proliferation, Silica particles",

author = "Anja Wittig and Helge Gehrke and \{Del Favero\}, Giorgia and Eva-Maria Fritz and Marco Al-Rawi and Silvia Diabate and Carsten Weiss and Haider Sami and Manfred Ogris and Doris Marko",

note = "Publisher Copyright: {\textcopyright} 2017 by the authors; licensee MDPI, Basel, Switzerland.",

year = "2017",

month = jan,

doi = "10.3390/nano7010018",

language = "English",

volume = "7",

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T1 - Amorphous Silica Particles Relevant in Food Industry Influence Cellular Growth and Associated Signaling Pathways in Human Gastric Carcinoma Cells

AU - Wittig, Anja

AU - Gehrke, Helge

AU - Del Favero, Giorgia

AU - Fritz, Eva-Maria

AU - Al-Rawi, Marco

AU - Diabate, Silvia

AU - Weiss, Carsten

AU - Sami, Haider

AU - Ogris, Manfred

AU - Marko, Doris

PY - 2017/1

Y1 - 2017/1

KW - silica particles

KW - cytotoxicity

KW - proliferation

KW - Ki-67

KW - EGFR and MAPK signaling

KW - gastrointestinal tract

KW - RECEPTOR TYROSINE KINASES

KW - LUNG EPITHELIAL-CELLS

KW - IN-VITRO TOXICITY

KW - OXIDATIVE STRESS

KW - GENE DELIVERY

KW - EGF RECEPTOR

KW - NANOPARTICLES

KW - APOPTOSIS

KW - PROLIFERATION

KW - ACTIVATION

KW - Cytotoxicity

KW - Gastrointestinal tract

KW - Proliferation

KW - Silica particles

UR - https://www.scopus.com/pages/publications/85009733747

U2 - 10.3390/nano7010018

DO - 10.3390/nano7010018

M3 - Article

SN - 2079-4991

VL - 7

JO - Nanomaterials

JF - Nanomaterials

IS - 1

M1 - 18

ER -

Amorphous Silica Particles Relevant in Food Industry Influence Cellular Growth and Associated Signaling Pathways in Human Gastric Carcinoma Cells

Funding

UN SDGs

Austrian Fields of Science 2012

Keywords

Access to Document

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