Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins

Patrick A H Ehm; Fabiola Lange; Carolin Hentschel; Anneke Jepsen; Madeleine Glück; Nina Nelson; Bettina Bettin; Christina de Bruyn Kops; Johannes Kirchmair; Marcus Nalaskowski; Manfred Jücker

doi:10.1016/j.cellsig.2019.109380

Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins

Patrick A H Ehm, Fabiola Lange, Carolin Hentschel, Anneke Jepsen, Madeleine Glück, Nina Nelson, Bettina Bettin, Christina de Bruyn Kops, Johannes Kirchmair, Marcus Nalaskowski, Manfred Jücker (Corresponding author)

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Article number	109380
Journal	Cellular signalling
Volume	63
DOIs	https://doi.org/10.1016/j.cellsig.2019.109380
Publication status	Published - Nov 2019
Externally published	Yes

Austrian Fields of Science 2012

106005 Bioinformatics
301207 Pharmaceutical chemistry

Keywords

Enzyme Stability
HEK293 Cells
Humans
Jurkat Cells
Mutation
Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases/chemistry
src Homology Domains/genetics
SH2 domain
RECOGNITION
PHOSPHATASE
SHIP1
FLVR motif
RECEPTOR
RESTORATION
CLONING
TUMOR-SUPPRESSOR SHIP1
Instability
MYELOID-LEUKEMIA
MUTATIONS
EXPRESSION
KINASES

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.cellsig.2019.109380

Cite this

@article{889973a6020b4cd69759cc3200dec4c1,

title = "Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins",

keywords = "Enzyme Stability, HEK293 Cells, Humans, Jurkat Cells, Mutation, Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases/chemistry, src Homology Domains/genetics, SH2 domain, RECOGNITION, PHOSPHATASE, SHIP1, FLVR motif, RECEPTOR, RESTORATION, CLONING, TUMOR-SUPPRESSOR SHIP1, Instability, MYELOID-LEUKEMIA, MUTATIONS, EXPRESSION, KINASES",

author = "Ehm, \{Patrick A H\} and Fabiola Lange and Carolin Hentschel and Anneke Jepsen and Madeleine Gl{\"u}ck and Nina Nelson and Bettina Bettin and \{de Bruyn Kops\}, Christina and Johannes Kirchmair and Marcus Nalaskowski and Manfred J{\"u}cker",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

month = nov,

doi = "10.1016/j.cellsig.2019.109380",

language = "English",

volume = "63",

journal = "Cellular signalling",

issn = "0898-6568",

}

TY - JOUR

T1 - Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins

AU - Ehm, Patrick A H

AU - Lange, Fabiola

AU - Hentschel, Carolin

AU - Jepsen, Anneke

AU - Glück, Madeleine

AU - Nelson, Nina

AU - Bettin, Bettina

AU - de Bruyn Kops, Christina

AU - Kirchmair, Johannes

AU - Nalaskowski, Marcus

AU - Jücker, Manfred

PY - 2019/11

Y1 - 2019/11

KW - Enzyme Stability

KW - HEK293 Cells

KW - Humans

KW - Jurkat Cells

KW - Mutation

KW - Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases/chemistry

KW - src Homology Domains/genetics

KW - SH2 domain

KW - RECOGNITION

KW - PHOSPHATASE

KW - SHIP1

KW - FLVR motif

KW - RECEPTOR

KW - RESTORATION

KW - CLONING

KW - TUMOR-SUPPRESSOR SHIP1

KW - Instability

KW - MYELOID-LEUKEMIA

KW - MUTATIONS

KW - EXPRESSION

KW - KINASES

UR - https://www.scopus.com/pages/publications/85070922996

U2 - 10.1016/j.cellsig.2019.109380

DO - 10.1016/j.cellsig.2019.109380

M3 - Article

C2 - 31377397

SN - 0898-6568

VL - 63

JO - Cellular signalling

JF - Cellular signalling

M1 - 109380

ER -

Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins

Austrian Fields of Science 2012

Keywords

UN SDGs

Access to Document

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Cite this