Animal snoRNAs and scaRNAs with exceptional structures

Manja Marz, Andreas Gruber, Christian Höner zu Siederdissen, Fabian Amman, Stefan Badelt, Sebastian Bartschat, Stephan Bernhart, Stephanie Kehr, Ronny Lorenz, Andrea Tanzer, Dilmurat Yusuf, Hakim Tafer, Ivo Hofacker, Peter Stadler (Corresponding author)

Publications: Contribution to journalArticlePeer Reviewed

Abstract

The overwhelming majority of small nucleolar RNAs (snoRNAs) fall into two clearly defined classes characterized by distinctive secondary structures and sequence motifs. A small group of diverse ncRNAs, however, shares the hallmarks of one or both classes of snoRNAs but differs substantially from the norm in some respects. Here, we compile the available information on these exceptional cases, conduct a thorough homology search throughout the available metazoan genomes, provide improved and expanded alignments, and investigate the evolutionary histories of these ncRNA families as well as their mutual relationships.
Original languageEnglish
Pages (from-to)938-946
Number of pages9
JournalRNA Biology
Volume8
Issue number6
Publication statusPublished - 2011

Austrian Fields of Science 2012

  • 106005 Bioinformatics
  • 104022 Theoretical chemistry

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