Anthropoid primate-specific retroviral element THE1B controls expression of CRH in placenta and alters gestation length

Caitlin E Dunn-Fletcher, Lisa M Muglia, Mihaela Pavlicev, Gernot Wolf, Ming-An Sun, Yueh-Chiang Hu, Elizabeth Huffman, Shivani Tumukuntala, Katri Thiele, Amrita Mukherjee, Sandra Zoubovsky, Xuzhe Zhang, Kayleigh A Swaggart, Katherine Y Bezold Lamm, Helen Jones, Todd S Macfarlan, Louis J Muglia

    Publications: Contribution to journalArticlePeer Reviewed

    Original languageEnglish
    Article numbere2006337
    Pages (from-to)e2006337
    Number of pages21
    JournalPLoS Biology
    Volume16
    Issue number9
    DOIs
    Publication statusPublished - Sep 2018

    Austrian Fields of Science 2012

    • 106012 Evolutionary research

    Keywords

    • Animals
    • Base Sequence
    • CRISPR-Cas Systems/genetics
    • Chromosomes, Artificial, Bacterial/genetics
    • Corticotropin-Releasing Hormone/genetics
    • Female
    • Gene Regulatory Networks
    • Homeodomain Proteins/metabolism
    • Humans
    • Male
    • Mice, Transgenic
    • Mutagenesis, Insertional/genetics
    • Parturition
    • Placenta/metabolism
    • Pregnancy
    • Primates/genetics
    • Protein Binding
    • Retroelements/genetics
    • Sequence Deletion
    • Species Specificity
    • Terminal Repeat Sequences/genetics
    • Transcription Factors/metabolism
    • Trophoblasts/metabolism
    • MESSENGER-RNA
    • HUMAN-PREGNANCY
    • GENE-EXPRESSION
    • HUMAN TROPHOBLAST
    • CORTICOTROPIN-RELEASING HORMONE
    • BIOCONDUCTOR PACKAGE
    • TRANSPOSABLE ELEMENTS
    • PRETERM BIRTH
    • ENDOGENOUS RETROVIRUS
    • MOUSE PLACENTA

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