Arabidopsis thaliana as a model organism for plant proteome research

Stefanie Wienkoop (Corresponding author), Sacha Baginsky, Wolfram Weckwerth

    Publications: Contribution to journalArticlePeer Reviewed

    Abstract

    Genome sequencing and systems biology revolutionized life sciences. Proteomics emerged as a fundamental technique of this novel research area. This review aims to summarize the contribution of Arabidopsis thaliana as a model organism for plants and the increasing impact of proteome research. Techniques for proteomics based on 2-DE and especially gel-free shotgun LC-MS/MS platforms have improved significantly during the last decades. Proteomics has proven to be complementary to other -omics techniques such as transcriptomics and metabolomics. Arabidopsis thaliana as one of the first model organisms worldwide, served in several of the most comprehensive studies for enhance genome annotation, profiling of organelles, tissues, cells or sub-cellular proteomes, as well as developmental processes and responses to biotic and abiotic stresses using differential relative and absolute quantitative strategies. Consequently, insights into plant proteome dynamics and cell functions are rapidly increasing. A proteomics-toolbox developed for systems biology research on Arabidopsis will be introduced.
    Original languageEnglish
    Pages (from-to)2239-2248
    Number of pages10
    JournalJournal of Proteomics
    Volume73
    Issue number11
    DOIs
    Publication statusPublished - 2010

    Austrian Fields of Science 2012

    • 106037 Proteomics
    • 106023 Molecular biology

    Fingerprint

    Dive into the research topics of 'Arabidopsis thaliana as a model organism for plant proteome research'. Together they form a unique fingerprint.

    Cite this