Asymmetric protected enoates as key intermediates towards an EPC synthesis of (+)-heptelidic acid

Gerhard Riehs; Ernst Urban

doi:10.1016/0040-4039(95)01538-S

Asymmetric protected enoates as key intermediates towards an EPC synthesis of (+)-heptelidic acid

Gerhard Riehs
, Ernst Urban

Department of Pharmaceutical Sciences

Publications: Contribution to journal › Article › Peer Reviewed

Abstract

Conjugate addition of (H₂C=CH)₂CuLi to 6n and 7n gave the adducts 9n (5′R,6′R) and 10n (5′S,6′R) as single diastereomers, respectively. Finally, the (5′R) configurated enoate 6n turned out to be valuable as a chiral building block for an EPC synthesis of (+)-heptelidic acid.

Original language	English
Pages (from-to)	7233-7234
Number of pages	2
Journal	Tetrahedron Letters
Volume	36
Issue number	40
DOIs	https://doi.org/10.1016/0040-4039(95)01538-S
Publication status	Published - 2 Oct 1995

Austrian Fields of Science 2012

301207 Pharmaceutical chemistry

Access to Document

10.1016/0040-4039(95)01538-S

Cite this

@article{27fd34ec33124ea79088c009e7b763e1,

title = "Asymmetric protected enoates as key intermediates towards an EPC synthesis of (+)-heptelidic acid",

abstract = "Conjugate addition of (H2C=CH)2CuLi to 6n and 7n gave the adducts 9n (5′R,6′R) and 10n (5′S,6′R) as single diastereomers, respectively. Finally, the (5′R) configurated enoate 6n turned out to be valuable as a chiral building block for an EPC synthesis of (+)-heptelidic acid.",

author = "Gerhard Riehs and Ernst Urban",

year = "1995",

month = oct,

day = "2",

doi = "10.1016/0040-4039(95)01538-S",

language = "English",

volume = "36",

pages = "7233--7234",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "PERGAMON-ELSEVIER SCIENCE LTD",

number = "40",

}

TY - JOUR

T1 - Asymmetric protected enoates as key intermediates towards an EPC synthesis of (+)-heptelidic acid

AU - Riehs, Gerhard

AU - Urban, Ernst

PY - 1995/10/2

Y1 - 1995/10/2

N2 - Conjugate addition of (H2C=CH)2CuLi to 6n and 7n gave the adducts 9n (5′R,6′R) and 10n (5′S,6′R) as single diastereomers, respectively. Finally, the (5′R) configurated enoate 6n turned out to be valuable as a chiral building block for an EPC synthesis of (+)-heptelidic acid.

AB - Conjugate addition of (H2C=CH)2CuLi to 6n and 7n gave the adducts 9n (5′R,6′R) and 10n (5′S,6′R) as single diastereomers, respectively. Finally, the (5′R) configurated enoate 6n turned out to be valuable as a chiral building block for an EPC synthesis of (+)-heptelidic acid.

UR - https://www.scopus.com/pages/publications/0029089622

U2 - 10.1016/0040-4039(95)01538-S

DO - 10.1016/0040-4039(95)01538-S

M3 - Article

AN - SCOPUS:0029089622

SN - 0040-4039

VL - 36

SP - 7233

EP - 7234

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 40

ER -

Asymmetric protected enoates as key intermediates towards an EPC synthesis of (+)-heptelidic acid

Abstract

Austrian Fields of Science 2012

Access to Document

Other files and links

Fingerprint

Cite this