Asymmetric synthesis of a structurally simplified analogue of the antibiotic heptelidic acid

Chemistry

• Asymmetric Synthesis 100%
• Carbene 100%
• Diastereomer 50%
• Ring Formation 50%
• Chiral Auxiliary 50%
• Triethylamine 50%
• Silyl 50%
• Reaction Step 50%
• Ketoester 50%
• Methyl Ester 50%
• Lactone Ring 50%
• Transesterification 50%