Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala

Juan Suarez; Sophia Khom; Francisco Alen; Luis A. Natividad; Florence P. Varodayan; Reesha R. Patel; Dean Kirson; Rocio Arco; Antonio Ballesta; Michal Bajo; Leticia Rubio; Remi Martin-Fardon; Fernando Rodriguez de Fonseca; Marisa Roberto

doi:10.1111/adb.12813

Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala

Juan Suarez
, Sophia Khom
, Francisco Alen
, Luis A. Natividad
, Florence P. Varodayan
, Reesha R. Patel
, Dean Kirson
, Rocio Arco
, Antonio Ballesta
, Michal Bajo
, Leticia Rubio
, Remi Martin-Fardon
, Fernando Rodriguez de Fonseca
, Marisa Roberto

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Article number	e12813
Number of pages	12
Journal	Addiction Biology
Volume	25
Issue number	5
DOIs	https://doi.org/10.1111/adb.12813
Publication status	Published - Sept 2020

Funding

Instituto de Salud Carlos III, Grant/Award Numbers: CPII17/00024, PI16/01374, PI16/01698 and RD16/0017/0001; Ministerio de Sanidad, Servicios Sociales e Igualdad, Grant/Award Numbers: PND2015/047, PND2018/044 and CAS16/00038; National Institutes of Health, Grant/Award Numbers: P60 AA006420, AA013498, AA021491, AA017447, AA015566, AA022249, AA024146, F32 AA026865, K99 AA026638, K99 AA025408 and K99 AA025393; Austrian Science Fund FWF, Grant/Award Number: J-3942-B30; National System of Health, ISCIII, ERDF-EU, Grant/Award Number: CPII17/00024; Instituto de Salud Carlos III (ISCIII), Ministerio de Economia y Competitividad (MINECO), and European Regional Development Funds - European Union (ERDF-EU), Grant/Award Numbers: PI16/01698, PI16/01374 and RD16/0017/0001; Ministerio de Educacion, Cultura y Deporte, Grant/Award Number: CAS16/00038

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Austrian Fields of Science 2012

301406 Neuropharmacology
301405 Neuropathology

Keywords

alcohol
amygdala
antidepressant
cannabinoid
glutamate
relapse
CANNABINOID CB1 RECEPTOR
CHRONIC ETHANOL
AMPA RECEPTOR
CONDITIONED REINSTATEMENT
PREFRONTAL CORTEX
AGONIST LY379268
ANIMAL-MODEL
RATS
WITHDRAWAL
DEPENDENCE

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10.1111/adb.12813

Cite this

Suarez, J., Khom, S., Alen, F., Natividad, L. A., Varodayan, F. P., Patel, R. R., Kirson, D., Arco, R., Ballesta, A., Bajo, M., Rubio, L., Martin-Fardon, R., Rodriguez de Fonseca, F., & Roberto, M. (2020). Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala. Addiction Biology, 25(5), Article e12813. https://doi.org/10.1111/adb.12813

@article{361965236dff4fa6b02febfd6e436a4a,

title = "Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala",

keywords = "alcohol, amygdala, antidepressant, cannabinoid, glutamate, relapse, CANNABINOID CB1 RECEPTOR, CHRONIC ETHANOL, AMPA RECEPTOR, CONDITIONED REINSTATEMENT, PREFRONTAL CORTEX, AGONIST LY379268, ANIMAL-MODEL, RATS, WITHDRAWAL, DEPENDENCE",

author = "Juan Suarez and Sophia Khom and Francisco Alen and Natividad, \{Luis A.\} and Varodayan, \{Florence P.\} and Patel, \{Reesha R.\} and Dean Kirson and Rocio Arco and Antonio Ballesta and Michal Bajo and Leticia Rubio and Remi Martin-Fardon and \{Rodriguez de Fonseca\}, Fernando and Marisa Roberto",

note = "Publisher Copyright: {\textcopyright} 2019 Society for the Study of Addiction",

year = "2020",

month = sep,

doi = "10.1111/adb.12813",

language = "English",

volume = "25",

journal = "Addiction Biology",

issn = "1355-6215",

publisher = "Wiley",

number = "5",

}

Suarez, J, Khom, S, Alen, F, Natividad, LA, Varodayan, FP, Patel, RR, Kirson, D, Arco, R, Ballesta, A, Bajo, M, Rubio, L, Martin-Fardon, R, Rodriguez de Fonseca, F & Roberto, M 2020, 'Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala', Addiction Biology, vol. 25, no. 5, e12813. https://doi.org/10.1111/adb.12813

TY - JOUR

T1 - Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala

AU - Suarez, Juan

AU - Khom, Sophia

AU - Alen, Francisco

AU - Natividad, Luis A.

AU - Varodayan, Florence P.

AU - Patel, Reesha R.

AU - Kirson, Dean

AU - Arco, Rocio

AU - Ballesta, Antonio

AU - Bajo, Michal

AU - Rubio, Leticia

AU - Martin-Fardon, Remi

AU - Rodriguez de Fonseca, Fernando

AU - Roberto, Marisa

PY - 2020/9

Y1 - 2020/9

KW - alcohol

KW - amygdala

KW - antidepressant

KW - cannabinoid

KW - glutamate

KW - relapse

KW - CANNABINOID CB1 RECEPTOR

KW - CHRONIC ETHANOL

KW - AMPA RECEPTOR

KW - CONDITIONED REINSTATEMENT

KW - PREFRONTAL CORTEX

KW - AGONIST LY379268

KW - ANIMAL-MODEL

KW - RATS

KW - WITHDRAWAL

KW - DEPENDENCE

UR - https://www.scopus.com/pages/publications/85069807467

U2 - 10.1111/adb.12813

DO - 10.1111/adb.12813

M3 - Article

SN - 1355-6215

VL - 25

JO - Addiction Biology

JF - Addiction Biology

IS - 5

M1 - e12813

ER -

Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala

Funding

UN SDGs

Austrian Fields of Science 2012

Keywords

Access to Document

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