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Class IV Lasso Peptides Synergistically Induce Proliferation of Cancer Cells and Sensitize Them to Doxorubicin

  • Jaime Felipe Guerrero-Garzón
  • , Eva Madland
  • , Martin Zehl
  • , Madhurendra Singh
  • , Shiva Rezaei
  • , Finn L. Aachmann
  • , Gaston Courtade
  • , Ernst Urban
  • , Christian Rückert
  • , Tobias Busche
  • , Jörn Kalinowski
  • , Yan Ru Cao
  • , Yi Jiang
  • , Cheng lin Jiang
  • , Galina Selivanova (Corresponding author)
  • , Sergey B. Zotchev (Corresponding author)

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Article number101785
Number of pages41
JournalIscience
Volume23
Issue number12
DOIs
Publication statusPublished - 18 Dec 2020

Funding

This study was supported by the University of Vienna , Swedish Research Council , Swedish Cancer Society , Bielefeld University , the University of Yunnan , NTNU Norwegian University of Science and Technology , and the grants from the Novo Nordisk Foundation ( NNF18OC0032242 ) and the Norwegian Research Council ( 226244 , 269408 ). We also acknowledge support by the Mass Spectrometry Center of the Faculty of Chemistry, University of Vienna .

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Austrian Fields of Science 2012

  • 106002 Biochemistry
  • 106013 Genetics
  • 104013 Natural product chemistry
  • 106022 Microbiology

Keywords

  • Biochemistry
  • Biological Sciences
  • Biotechnology
  • Microbiology
  • MECHANISM
  • MICROCIN J25
  • STABILITY
  • HETEROLOGOUS EXPRESSION

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