Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca(2+) signalling

Serena Stadler; Huu Chi Nguyen; Helga Schachner; Daniela Milovanovic; Silvio Holzner; Stefan Brenner; Julia Eichsteininger; Mira Stadler; Daniel Senfter; Liselotte Krenn; Wolfgang M Schmidt; Nicole Huttary; Sigurd Krieger; Oskar Koperek; Zsuzsanna Bago-Horvath; Konstantin Alexander Brendel; Brigitte Marian; Oliver de Wever; Robert M Mader; Benedikt Giessrigl; Walter Jäger; Helmut Dolznig; Georg Krupitza

doi:10.1007/s00018-016-2441-5

Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca(2+) signalling

Serena Stadler, Huu Chi Nguyen, Helga Schachner, Daniela Milovanovic, Silvio Holzner, Stefan Brenner, Julia Eichsteininger, Mira Stadler, Daniel Senfter, Liselotte Krenn, Wolfgang M Schmidt, Nicole Huttary, Sigurd Krieger, Oskar Koperek, Zsuzsanna Bago-Horvath, Konstantin Alexander Brendel, Brigitte Marian, Oliver de Wever, Robert M Mader, Benedikt GiessriglWalter Jäger, Helmut Dolznig, Georg Krupitza

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Pages (from-to)	1907-1921
Number of pages	15
Journal	Cellular and Molecular Life Sciences
Volume	74
Issue number	10
Early online date	24 Dec 2016
DOIs	https://doi.org/10.1007/s00018-016-2441-5
Publication status	Published - May 2017

Austrian Fields of Science 2012

301209 Pharmacy

Keywords

3D invasion model
ACTIVATION
ARACHIDONIC-ACID
Arachidonic acid metabolite
CAMP PRODUCTION
ECM
ENDOTHELIAL-CELLS
EXPRESSION
IN-VITRO
INTRAVASATION
LIGHT-CHAIN KINASE
PHOSPHOLIPASE-C-EPSILON
RECEPTOR
Signal transduction
Tumour progression

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s00018-016-2441-5

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Stadler, S., Nguyen, H. C., Schachner, H., Milovanovic, D., Holzner, S., Brenner, S., Eichsteininger, J., Stadler, M., Senfter, D., Krenn, L., Schmidt, W. M., Huttary, N., Krieger, S., Koperek, O., Bago-Horvath, Z., Brendel, K. A., Marian, B., de Wever, O., Mader, R. M., ... Krupitza, G. (2017). Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca(2+) signalling. Cellular and Molecular Life Sciences, 74(10), 1907-1921. https://doi.org/10.1007/s00018-016-2441-5

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title = "Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca(2+) signalling",

keywords = "3D invasion model, ACTIVATION, ARACHIDONIC-ACID, Arachidonic acid metabolite, CAMP PRODUCTION, ECM, ENDOTHELIAL-CELLS, EXPRESSION, IN-VITRO, INTRAVASATION, LIGHT-CHAIN KINASE, PHOSPHOLIPASE-C-EPSILON, RECEPTOR, Signal transduction, Tumour progression",

author = "Serena Stadler and Nguyen, {Huu Chi} and Helga Schachner and Daniela Milovanovic and Silvio Holzner and Stefan Brenner and Julia Eichsteininger and Mira Stadler and Daniel Senfter and Liselotte Krenn and Schmidt, {Wolfgang M} and Nicole Huttary and Sigurd Krieger and Oskar Koperek and Zsuzsanna Bago-Horvath and Brendel, {Konstantin Alexander} and Brigitte Marian and {de Wever}, Oliver and Mader, {Robert M} and Benedikt Giessrigl and Walter J{\"a}ger and Helmut Dolznig and Georg Krupitza",

note = "Publisher Copyright: {\textcopyright} 2017, The Author(s).",

year = "2017",

month = may,

doi = "10.1007/s00018-016-2441-5",

language = "English",

volume = "74",

pages = "1907--1921",

journal = "Cellular and Molecular Life Sciences",

issn = "1420-682X",

publisher = "SPRINGER BASEL AG",

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Stadler, S, Nguyen, HC, Schachner, H, Milovanovic, D, Holzner, S, Brenner, S, Eichsteininger, J, Stadler, M, Senfter, D, Krenn, L, Schmidt, WM, Huttary, N, Krieger, S, Koperek, O, Bago-Horvath, Z, Brendel, KA, Marian, B, de Wever, O, Mader, RM, Giessrigl, B, Jäger, W , Dolznig, H & Krupitza, G 2017, 'Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca(2+) signalling', Cellular and Molecular Life Sciences, vol. 74, no. 10, pp. 1907-1921. https://doi.org/10.1007/s00018-016-2441-5

TY - JOUR

T1 - Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca(2+) signalling

AU - Stadler, Serena

AU - Nguyen, Huu Chi

AU - Schachner, Helga

AU - Milovanovic, Daniela

AU - Holzner, Silvio

AU - Brenner, Stefan

AU - Eichsteininger, Julia

AU - Stadler, Mira

AU - Senfter, Daniel

AU - Krenn, Liselotte

AU - Schmidt, Wolfgang M

AU - Huttary, Nicole

AU - Krieger, Sigurd

AU - Koperek, Oskar

AU - Bago-Horvath, Zsuzsanna

AU - Brendel, Konstantin Alexander

AU - Marian, Brigitte

AU - de Wever, Oliver

AU - Mader, Robert M

AU - Giessrigl, Benedikt

AU - Jäger, Walter

AU - Dolznig, Helmut

AU - Krupitza, Georg

PY - 2017/5

Y1 - 2017/5

KW - 3D invasion model

KW - ACTIVATION

KW - ARACHIDONIC-ACID

KW - Arachidonic acid metabolite

KW - CAMP PRODUCTION

KW - ECM

KW - ENDOTHELIAL-CELLS

KW - EXPRESSION

KW - IN-VITRO

KW - INTRAVASATION

KW - LIGHT-CHAIN KINASE

KW - PHOSPHOLIPASE-C-EPSILON

KW - RECEPTOR

KW - Signal transduction

KW - Tumour progression

UR - http://www.scopus.com/inward/record.url?scp=85007201959&partnerID=8YFLogxK

U2 - 10.1007/s00018-016-2441-5

DO - 10.1007/s00018-016-2441-5

M3 - Article

C2 - 28013338

SN - 1420-682X

VL - 74

SP - 1907

EP - 1921

JO - Cellular and Molecular Life Sciences

JF - Cellular and Molecular Life Sciences

IS - 10

ER -

Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca(2+) signalling

Austrian Fields of Science 2012

Keywords

UN SDGs

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