Coupling of the engineered DNA "mutator" to a biosensor as a new paradigm for activation of silent biosynthetic gene clusters in Streptomyces

Olga N. Sekurova, Yi-Qian Sun, Martin Zehl, Christian Rueckert, Anna Stich, Tobias Busche, Joern Kalinowski, Sergey B. Zotchev (Corresponding author)

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Pages (from-to)8396-8405
Number of pages10
JournalNucleic Acids Research
Volume49
Issue number14
Early online date1 Jul 2021
DOIs
Publication statusPublished - 20 Aug 2021

Austrian Fields of Science 2012

  • 106002 Biochemistry
  • 106023 Molecular biology
  • 301207 Pharmaceutical chemistry
  • 301204 Pharmacognosy

Keywords

  • ESCHERICHIA-COLI
  • POLYMERASE-III
  • NATURAL-PRODUCTS
  • GENOME SEQUENCE
  • EPSILON-SUBUNIT
  • REPLICATION
  • MUTATIONS
  • GENERATION
  • EXPRESSION
  • DISCOVERY

Fingerprint

Dive into the research topics of 'Coupling of the engineered DNA "mutator" to a biosensor as a new paradigm for activation of silent biosynthetic gene clusters in Streptomyces'. Together they form a unique fingerprint.

Cite this