Design, Synthesis, and Biological Evaluation of 4,4’-Difluorobenzhydrol Carbamates as Selective M1 Antagonists

Jonas Kilian, Marius Ozenil, Marlon Millard, Dorka Fürtös, Verena Maisetschläger, Wolfgang Holzer, Wolfgang Wadsak, Marcus Hacker, Thierry Langer, Verena Pichler

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Article number248
Number of pages18
JournalPharmaceuticals
Volume15
Issue number2
DOIs
Publication statusPublished - Feb 2022

Austrian Fields of Science 2012

  • 104015 Organic chemistry

Keywords

  • Drug development
  • Molecular docking
  • Muscarinic acetylcholine receptors
  • Subtype selectivity
  • DRUG
  • subtype selectivity
  • ALLOSTERIC MODULATORS
  • M1
  • muscarinic acetylcholine receptors
  • drug development
  • MUSCARINIC ACETYLCHOLINE-RECEPTORS
  • LOGP
  • molecular docking
  • LIGANDS
  • AGONIST

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