Discovery of nonsteroidal 17 beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries

Daniela Schuster; Lyubomir G. Nashev; Johannes Kirchmair; Christian Laggner; Gerhard Wolber; Thierry Langer; Alex Odermatt

doi:10.1021/jm800054h

Discovery of nonsteroidal 17 beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries

Daniela Schuster
, Lyubomir G. Nashev
, Johannes Kirchmair
, Christian Laggner
, Gerhard Wolber
, Thierry Langer
, Alex Odermatt

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Pages (from-to)	4188-4199
Number of pages	12
Journal	Journal of Medicinal Chemistry
Volume	51
Issue number	14
DOIs	https://doi.org/10.1021/jm800054h
Publication status	Published - 24 Jul 2008
Externally published	Yes

Austrian Fields of Science 2012

301207 Pharmaceutical chemistry

Keywords

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1
17-BETA-HYDROXY STEROID DEHYDROGENASE
3D QSAR MODEL
BREAST-CANCER
POTENT INHIBITORS
ACTIVE-SITE
PROGNOSTIC-SIGNIFICANCE
ESTRADIOL
PROTEIN
DESIGN

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/jm800054h

Cite this

@article{c0a573a6b07d4a3f98d292b5bd3b44b4,

title = "Discovery of nonsteroidal 17 beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries",

keywords = "11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1, 17-BETA-HYDROXY STEROID DEHYDROGENASE, 3D QSAR MODEL, BREAST-CANCER, POTENT INHIBITORS, ACTIVE-SITE, PROGNOSTIC-SIGNIFICANCE, ESTRADIOL, PROTEIN, DESIGN",

author = "Daniela Schuster and Nashev, \{Lyubomir G.\} and Johannes Kirchmair and Christian Laggner and Gerhard Wolber and Thierry Langer and Alex Odermatt",

year = "2008",

month = jul,

day = "24",

doi = "10.1021/jm800054h",

language = "English",

volume = "51",

pages = "4188--4199",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "AMER CHEMICAL SOC",

number = "14",

}

TY - JOUR

T1 - Discovery of nonsteroidal 17 beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries

AU - Schuster, Daniela

AU - Nashev, Lyubomir G.

AU - Kirchmair, Johannes

AU - Laggner, Christian

AU - Wolber, Gerhard

AU - Langer, Thierry

AU - Odermatt, Alex

PY - 2008/7/24

Y1 - 2008/7/24

KW - 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1

KW - 17-BETA-HYDROXY STEROID DEHYDROGENASE

KW - 3D QSAR MODEL

KW - BREAST-CANCER

KW - POTENT INHIBITORS

KW - ACTIVE-SITE

KW - PROGNOSTIC-SIGNIFICANCE

KW - ESTRADIOL

KW - PROTEIN

KW - DESIGN

U2 - 10.1021/jm800054h

DO - 10.1021/jm800054h

M3 - Article

SN - 0022-2623

VL - 51

SP - 4188

EP - 4199

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 14

ER -

Discovery of nonsteroidal 17 beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries

Austrian Fields of Science 2012

Keywords

UN SDGs

Access to Document

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Cite this