Discovery of novel cathepsin S inhibitors by pharmacophore-based virtual high-throughput screening

Patrick Markt; Caroline McGoohan; Brian Walker; Johannes Kirchmair; C. Lemens Feldmann; Gabriella De Martino; Gudrun Spitzer; Simona Distinto; Daniela Schuster; Gerhard Wolber; Christian Laggner; Thierry Langer

doi:10.1021/ci800101j

Discovery of novel cathepsin S inhibitors by pharmacophore-based virtual high-throughput screening

Patrick Markt, Caroline McGoohan, Brian Walker, Johannes Kirchmair, C. Lemens Feldmann, Gabriella De Martino, Gudrun Spitzer, Simona Distinto, Daniela Schuster, Gerhard Wolber, Christian Laggner, Thierry Langer

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Pages (from-to)	1693-1705
Number of pages	13
Journal	Journal of Chemical Information and Modeling
Volume	48
Issue number	8
DOIs	https://doi.org/10.1021/ci800101j
Publication status	Published - Aug 2008
Externally published	Yes

Austrian Fields of Science 2012

301207 Pharmaceutical chemistry

Keywords

K INHIBITORS
NONCOVALENT INHIBITORS
ARYLAMINOETHYL AMIDES
CYSTEINE PROTEASES
DESIGN
POTENT
DOCKING
BINDING
MODELS
SERIES

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/ci800101j

Cite this

@article{a680c61a57974d25bf653fcbc90d979d,

title = "Discovery of novel cathepsin S inhibitors by pharmacophore-based virtual high-throughput screening",

keywords = "K INHIBITORS, NONCOVALENT INHIBITORS, ARYLAMINOETHYL AMIDES, CYSTEINE PROTEASES, DESIGN, POTENT, DOCKING, BINDING, MODELS, SERIES",

author = "Patrick Markt and Caroline McGoohan and Brian Walker and Johannes Kirchmair and Feldmann, \{C. Lemens\} and \{De Martino\}, Gabriella and Gudrun Spitzer and Simona Distinto and Daniela Schuster and Gerhard Wolber and Christian Laggner and Thierry Langer",

year = "2008",

month = aug,

doi = "10.1021/ci800101j",

language = "English",

volume = "48",

pages = "1693--1705",

journal = "Journal of Chemical Information and Modeling",

issn = "1549-9596",

publisher = "AMER CHEMICAL SOC",

number = "8",

}

TY - JOUR

T1 - Discovery of novel cathepsin S inhibitors by pharmacophore-based virtual high-throughput screening

AU - Markt, Patrick

AU - McGoohan, Caroline

AU - Walker, Brian

AU - Kirchmair, Johannes

AU - Feldmann, C. Lemens

AU - De Martino, Gabriella

AU - Spitzer, Gudrun

AU - Distinto, Simona

AU - Schuster, Daniela

AU - Wolber, Gerhard

AU - Laggner, Christian

AU - Langer, Thierry

PY - 2008/8

Y1 - 2008/8

KW - K INHIBITORS

KW - NONCOVALENT INHIBITORS

KW - ARYLAMINOETHYL AMIDES

KW - CYSTEINE PROTEASES

KW - DESIGN

KW - POTENT

KW - DOCKING

KW - BINDING

KW - MODELS

KW - SERIES

U2 - 10.1021/ci800101j

DO - 10.1021/ci800101j

M3 - Article

SN - 1549-9596

VL - 48

SP - 1693

EP - 1705

JO - Journal of Chemical Information and Modeling

JF - Journal of Chemical Information and Modeling

IS - 8

ER -

Discovery of novel cathepsin S inhibitors by pharmacophore-based virtual high-throughput screening

Austrian Fields of Science 2012

Keywords

UN SDGs

Access to Document

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Cite this