Discrimination between 34 of 36 possible combinations of three C>T SNP genotypes in the MGMT promoter by high resolution melting analysis coupled with pyrosequencing using a single primer set

Katja Zappe, Christine Pirker, Heidi Miedl, Martin Schreiber, Petra Heffeter, Georg Pfeiler, Stefan Hacker, Werner Haslik, Sabine Spiegl-Kreinecker, Margit Cichna-Markl (Corresponding author)

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Article number12527
Number of pages27
JournalInternational Journal of Molecular Sciences
Volume22
Issue number22
DOIs
Publication statusPublished - Nov 2021

Austrian Fields of Science 2012

  • 106023 Molecular biology
  • 104002 Analytical chemistry

Keywords

  • Genotyping
  • High resolution melting
  • MGMT
  • Multiple SNPs
  • Pyrosequencing
  • METHYLATION
  • high resolution melting
  • genotyping
  • pyrosequencing
  • NUCLEOTIDE POLYMORPHISMS
  • IDENTIFICATION
  • CANCER
  • CYTOGENETIC CHARACTERIZATION
  • GENOME
  • GLIOBLASTOMA
  • GENE
  • RS16906252
  • multiple SNPs
  • CURVE ANALYSIS

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