Doublecortin and IGF-1R protein levels are reduced in spite of unchanged DNA methylation in the hippocampus of aged rats

Georg Pretsch, Nasim Sanadgol, Roman Smidak, Jana Lubec, Volker Korz, Harald Hoeger, Katja Zappe, Margit Cichna-Markl (Corresponding author), Gert Lubec (Corresponding author)

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Pages (from-to)543–553
Number of pages11
JournalAmino Acids
Volume52
Issue number4
DOIs
Publication statusPublished - 1 Apr 2020

Austrian Fields of Science 2012

  • 106002 Biochemistry
  • 106023 Molecular biology
  • 104002 Analytical chemistry

Keywords

  • Aging
  • Doublecortin
  • IGF-1R
  • mGluR5
  • Hippocampus
  • DNA methylation
  • GROWTH-FACTOR-I
  • METABOTROPIC GLUTAMATE RECEPTORS
  • MESSENGER-RNA
  • GENE-THERAPY
  • LIFE-SPAN
  • INSULIN
  • BRAIN
  • EXPRESSION
  • NEUROGENESIS
  • DECLINE

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