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Drug Nanocarriers Labeled With Near-infrared-emitting Quantum Dots (Quantoplexes): Imaging Fast Dynamics of Distribution in Living Animals

  • Arkadi Zintchenko
  • , Andrei S. Susha
  • , Massimo Concia
  • , Jochen Feldmann
  • , Ernst Wagner
  • , Andrey L. Rogach
  • , Manfred Ogris

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Pages (from-to)1849-1856
Number of pages8
JournalMolecular Therapy
Volume17
Issue number11
DOIs
Publication statusPublished - Nov 2009
Externally publishedYes

Funding

This work was supported by the EC funded project GIANT, the DFG SFB486 and SPP1230, the DFG Excellence Cluster "Nanosystems Initiative Munich" (NIM) and the LMU excellent program. Melinda Kiss is gratefully acknowledged for cloning of plasmid pCpG-LucSh. We thank Dr Martin Schleef from Plasmid Factory for providing pCpGLucSh in "ccc" quality. Prof Don C. Lamb is greatly acknowledged for careful review of the manuscript.

Austrian Fields of Science 2012

  • 301207 Pharmaceutical chemistry

Keywords

  • IN-VIVO
  • GENE-TRANSFER
  • PLASMID DNA
  • COMPLEXES
  • DELIVERY
  • BIODISTRIBUTION
  • NANOCRYSTALS
  • NANOPARTICLES
  • CIRCULATION
  • STABILITY

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