Dynamics of the EAG1 K+ channel selectivity filter assessed by molecular dynamics simulations

Harald Bernsteiner; Michael Bründl; Anna Stary-Weinzinger

doi:10.1016/j.bbrc.2017.01.064

Dynamics of the EAG1 K+ channel selectivity filter assessed by molecular dynamics simulations

Harald Bernsteiner
, Michael Bründl
, Anna Stary-Weinzinger (Corresponding author)

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Pages (from-to)	107-112
Number of pages	6
Journal	Biochemical and Biophysical Research Communications
Volume	484
Issue number	1
DOIs	https://doi.org/10.1016/j.bbrc.2017.01.064
Publication status	Published - 26 Feb 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Austrian Fields of Science 2012

301206 Pharmacology

Keywords

Cryoelectron Microscopy
Ether-A-Go-Go Potassium Channels
Humans
Molecular Dynamics Simulation
Journal Article
Research Support, Non-U.S. Gov't
ACTIVATION
KCNH1 channel
Na+ binding sites
C-TYPE INACTIVATION
MECHANISM
C-type inactivation
Y464A mutant
Molecular dynamics simulation
PARAMETERS
INSIGHT
HYDRATION
KIRBAC1.1
Ion binding sites
HERG POTASSIUM CHANNEL
ION PERMEATION
MUTATIONS
Na binding sites

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10.1016/j.bbrc.2017.01.064Licence: CC BY-NC-ND 4.0

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keywords = "Cryoelectron Microscopy, Ether-A-Go-Go Potassium Channels, Humans, Molecular Dynamics Simulation, Journal Article, Research Support, Non-U.S. Gov't, ACTIVATION, KCNH1 channel, Na+ binding sites, C-TYPE INACTIVATION, MECHANISM, C-type inactivation, Y464A mutant, Molecular dynamics simulation, PARAMETERS, INSIGHT, HYDRATION, KIRBAC1.1, Ion binding sites, HERG POTASSIUM CHANNEL, ION PERMEATION, MUTATIONS, Na binding sites",

author = "Harald Bernsteiner and Michael Br{\"u}ndl and Anna Stary-Weinzinger",

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year = "2017",

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doi = "10.1016/j.bbrc.2017.01.064",

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AU - Bernsteiner, Harald

AU - Bründl, Michael

AU - Stary-Weinzinger, Anna

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KW - Cryoelectron Microscopy

KW - Ether-A-Go-Go Potassium Channels

KW - Humans

KW - Molecular Dynamics Simulation

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

KW - ACTIVATION

KW - KCNH1 channel

KW - Na+ binding sites

KW - C-TYPE INACTIVATION

KW - MECHANISM

KW - C-type inactivation

KW - Y464A mutant

KW - Molecular dynamics simulation

KW - PARAMETERS

KW - INSIGHT

KW - HYDRATION

KW - KIRBAC1.1

KW - Ion binding sites

KW - HERG POTASSIUM CHANNEL

KW - ION PERMEATION

KW - MUTATIONS

KW - Na binding sites

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SP - 107

EP - 112

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

IS - 1

ER -

Dynamics of the EAG1 K+ channel selectivity filter assessed by molecular dynamics simulations

UN SDGs

Austrian Fields of Science 2012

Keywords

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