Electrophoretic purification of tumor-targeted polyethylenimine-based polyplexes reduces toxic side effects in vivo

Julia Fahrmeir; Michael Gunther; Nicole Tietze; Ernst Wagner; Manfred Ogris

doi:10.1016/j.jconrel.2007.05.013

Electrophoretic purification of tumor-targeted polyethylenimine-based polyplexes reduces toxic side effects in vivo

Julia Fahrmeir
, Michael Gunther
, Nicole Tietze
, Ernst Wagner
, Manfred Ogris (Corresponding author)

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Pages (from-to)	236-245
Number of pages	10
Journal	Journal of Controlled Release
Volume	122
Issue number	3
DOIs	https://doi.org/10.1016/j.jconrel.2007.05.013
Publication status	Published - 8 Oct 2007
Externally published	Yes
Event	13th International Symposium on Recent Advances in Drug Delivery - Salt Lake City, United States Duration: 26 Feb 2007 → 28 Feb 2007

Austrian Fields of Science 2012

301207 Pharmaceutical chemistry

Keywords

non-viral gene delivery
electrophoresis
biocompatibility
polyplex purification
tumor targeting
DNA/TRANSFERRIN-PEI COMPLEXES
GENE DELIVERY
LINEAR POLYETHYLENIMINE
DNA COMPLEXES
PLASMID DNA
TRANSFECTION
MICE
OLIGONUCLEOTIDE
EXPRESSION
INJECTION

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10.1016/j.jconrel.2007.05.013

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@article{77fc99588c914d63af36b14858b83b10,

title = "Electrophoretic purification of tumor-targeted polyethylenimine-based polyplexes reduces toxic side effects in vivo",

keywords = "non-viral gene delivery, electrophoresis, biocompatibility, polyplex purification, tumor targeting, DNA/TRANSFERRIN-PEI COMPLEXES, GENE DELIVERY, LINEAR POLYETHYLENIMINE, DNA COMPLEXES, PLASMID DNA, TRANSFECTION, MICE, OLIGONUCLEOTIDE, EXPRESSION, INJECTION",

author = "Julia Fahrmeir and Michael Gunther and Nicole Tietze and Ernst Wagner and Manfred Ogris",

year = "2007",

month = oct,

day = "8",

doi = "10.1016/j.jconrel.2007.05.013",

language = "English",

volume = "122",

pages = "236--245",

journal = "Journal of Controlled Release",

issn = "0168-3659",

publisher = "ELSEVIER SCIENCE BV",

number = "3",

note = "13th International Symposium on Recent Advances in Drug Delivery ; Conference date: 26-02-2007 Through 28-02-2007",

}

TY - JOUR

T1 - Electrophoretic purification of tumor-targeted polyethylenimine-based polyplexes reduces toxic side effects in vivo

AU - Fahrmeir, Julia

AU - Gunther, Michael

AU - Tietze, Nicole

AU - Wagner, Ernst

AU - Ogris, Manfred

PY - 2007/10/8

Y1 - 2007/10/8

KW - non-viral gene delivery

KW - electrophoresis

KW - biocompatibility

KW - polyplex purification

KW - tumor targeting

KW - DNA/TRANSFERRIN-PEI COMPLEXES

KW - GENE DELIVERY

KW - LINEAR POLYETHYLENIMINE

KW - DNA COMPLEXES

KW - PLASMID DNA

KW - TRANSFECTION

KW - MICE

KW - OLIGONUCLEOTIDE

KW - EXPRESSION

KW - INJECTION

U2 - 10.1016/j.jconrel.2007.05.013

DO - 10.1016/j.jconrel.2007.05.013

M3 - Article

SN - 0168-3659

VL - 122

SP - 236

EP - 245

JO - Journal of Controlled Release

JF - Journal of Controlled Release

IS - 3

T2 - 13th International Symposium on Recent Advances in Drug Delivery

Y2 - 26 February 2007 through 28 February 2007

ER -

Electrophoretic purification of tumor-targeted polyethylenimine-based polyplexes reduces toxic side effects in vivo

Austrian Fields of Science 2012

Keywords

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