Enhanced arecoline derivatives as muscarinic acetylcholine receptor M1 ligands for potential application as PET radiotracers

Marius Ozenil; Katharina Pacher; Theresa Balber; Chrysoula Vraka; Alexander Roller; Wolfgang Holzer; Helmut Spreitzer; Markus Mitterhauser; Wolfgang Wadsak; Marcus Hacker; Verena Pichler

doi:10.1016/j.ejmech.2020.112623

Enhanced arecoline derivatives as muscarinic acetylcholine receptor M1 ligands for potential application as PET radiotracers

Marius Ozenil
, Katharina Pacher
, Theresa Balber
, Chrysoula Vraka
, Alexander Roller
, Wolfgang Holzer
, Helmut Spreitzer
, Markus Mitterhauser
, Wolfgang Wadsak
, Marcus Hacker (Corresponding author)
, Verena Pichler (Corresponding author)

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Article number	112623
Number of pages	18
Journal	European Journal of Medicinal Chemistry
Volume	204
DOIs	https://doi.org/10.1016/j.ejmech.2020.112623
Publication status	Published - 15 Oct 2020

Funding

Funding was provided by the Medical University of Vienna and University of Vienna.

Austrian Fields of Science 2012

301209 Pharmacy
301305 Medical chemistry
301206 Pharmacology

Keywords

Muscarinic acetylcholine receptors
PET
Carbon-11
Neuroimaging
HUMAN BRAIN
ARECAIDINE
AGONIST
LOGP
OPPORTUNITIES
GUVACINE
SUBTYPES

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10.1016/j.ejmech.2020.112623

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Ozenil, M., Pacher, K., Balber, T., Vraka, C., Roller, A., Holzer, W., Spreitzer, H., Mitterhauser, M., Wadsak, W., Hacker, M., & Pichler, V. (2020). Enhanced arecoline derivatives as muscarinic acetylcholine receptor M1 ligands for potential application as PET radiotracers. European Journal of Medicinal Chemistry, 204, Article 112623. https://doi.org/10.1016/j.ejmech.2020.112623

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AU - Ozenil, Marius

AU - Pacher, Katharina

AU - Balber, Theresa

AU - Vraka, Chrysoula

AU - Roller, Alexander

AU - Holzer, Wolfgang

AU - Spreitzer, Helmut

AU - Mitterhauser, Markus

AU - Wadsak, Wolfgang

AU - Hacker, Marcus

AU - Pichler, Verena

PY - 2020/10/15

Y1 - 2020/10/15

KW - Muscarinic acetylcholine receptors

KW - PET

KW - Carbon-11

KW - Neuroimaging

KW - HUMAN BRAIN

KW - ARECAIDINE

KW - AGONIST

KW - LOGP

KW - OPPORTUNITIES

KW - GUVACINE

KW - SUBTYPES

UR - https://www.scopus.com/pages/publications/85088290590

U2 - 10.1016/j.ejmech.2020.112623

DO - 10.1016/j.ejmech.2020.112623

M3 - Article

SN - 0223-5234

VL - 204

JO - European Journal of Medicinal Chemistry

JF - European Journal of Medicinal Chemistry

M1 - 112623

ER -

Enhanced arecoline derivatives as muscarinic acetylcholine receptor M1 ligands for potential application as PET radiotracers

Funding

Austrian Fields of Science 2012

Keywords

Access to Document

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